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Pexmetinib suppresses osteoclast formation and breast cancer induced osteolysis via P38/STAT3 signal pathway

Breast cancer metastases to the bone can lead to a series of bone-related events that seriously affect the quality of life. Pexmetinib, a novel p38 mitogen-activated protein kinase (p38) inhibitor that has been evaluated in phase I clinical trials for myelodysplastic syndrome, but the effects of Pex...

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Detalles Bibliográficos
Autores principales:	Jie, Zhiwei, Wang, Shiyu, Ma, Qingliang, Shen, Yang, Zhao, Xiangde, Yu, Hejun, Xie, Ziang, Jiang, Chao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253705/ https://www.ncbi.nlm.nih.gov/pubmed/35800294 http://dx.doi.org/10.1016/j.jbo.2022.100439

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