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Identification of lysine-lactylated substrates in gastric cancer cells

Cancer cells tend to utilize aerobic glycolysis to generate energy and metabolites; the end product of aerobic glycolysis is lactate, which promotes lysine lactylation (Kla). Kla is a newly discovered histone post-translational modification (PTM) that plays important roles in regulating gene express...

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Detalles Bibliográficos
Autores principales:	Yang, Dawei, Yin, Jie, Shan, Liuqun, Yi, Xingling, Zhang, Wei, Ding, Yongbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253728/ https://www.ncbi.nlm.nih.gov/pubmed/35800753 http://dx.doi.org/10.1016/j.isci.2022.104630

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