The C-Terminal Domain of Y-Box Binding Protein 1 Exhibits Structure-Specific Binding to Poly(ADP-Ribose), Which Regulates PARP1 Activity

Y-box-binding protein 1 (YB-1) is a multifunctional protein involved in the regulation of gene expression. Recent studies showed that in addition to its role in the RNA and DNA metabolism, YB-1 is involved in the regulation of PARP1 activity, which catalyzes poly(ADP-ribose) [PAR] synthesis under ge...

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Detalles Bibliográficos
Autores principales: Naumenko, Konstantin N., Sukhanova, Mariya V., Hamon, Loic, Kurgina, Tatyana A., Anarbaev, Rashid O., Mangerich, Aswin, Pastré, David, Lavrik, Olga I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253770/
https://www.ncbi.nlm.nih.gov/pubmed/35800891
http://dx.doi.org/10.3389/fcell.2022.831741

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