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Prior statin and short‐term outcomes of primary intracerebral hemorrhage: From a large‐scale nationwide longitudinal registry
INTRODUCTION: The relationship between statins and intracerebral hemorrhage outcomes is unclear. AIM: We aimed to compare the in‐hospital mortality and evacuation of intracranial hematoma rates in patients with primary intracerebral hemorrhage between prior statin users and nonusers. RESULTS: The fi...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253784/ https://www.ncbi.nlm.nih.gov/pubmed/35603937 http://dx.doi.org/10.1111/cns.13868 |
Sumario: | INTRODUCTION: The relationship between statins and intracerebral hemorrhage outcomes is unclear. AIM: We aimed to compare the in‐hospital mortality and evacuation of intracranial hematoma rates in patients with primary intracerebral hemorrhage between prior statin users and nonusers. RESULTS: The final study population included 66,263 patients. Multivariable logistics analyses showed that prior statin use was not associated with in‐hospital mortality for primary intracerebral hemorrhage (adjusted odd ratio 0.78, 95% CI 0.61–1.01), but reduced the proportion of patients undergoing evacuation of intracranial hematoma (adjusted odd ratio 0.70, 95% CI 0.61–0.82). Propensity score matching analyses yielded similar results. CONCLUSION: Prior statin use was not associated with in‐hospital mortality but did reduce evacuation of intracranial hematoma rates. |
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