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Prior statin and short‐term outcomes of primary intracerebral hemorrhage: From a large‐scale nationwide longitudinal registry

INTRODUCTION: The relationship between statins and intracerebral hemorrhage outcomes is unclear. AIM: We aimed to compare the in‐hospital mortality and evacuation of intracranial hematoma rates in patients with primary intracerebral hemorrhage between prior statin users and nonusers. RESULTS: The fi...

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Detalles Bibliográficos
Autores principales: Li, Guangshuo, Wang, Shang, Xiong, Yunyun, Gu, Hongqiu, Yang, Kaixuan, Yang, Xin, Wang, Chunjuan, Wang, Chuanying, Li, Zixiao, Zhao, Xingquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253784/
https://www.ncbi.nlm.nih.gov/pubmed/35603937
http://dx.doi.org/10.1111/cns.13868
Descripción
Sumario:INTRODUCTION: The relationship between statins and intracerebral hemorrhage outcomes is unclear. AIM: We aimed to compare the in‐hospital mortality and evacuation of intracranial hematoma rates in patients with primary intracerebral hemorrhage between prior statin users and nonusers. RESULTS: The final study population included 66,263 patients. Multivariable logistics analyses showed that prior statin use was not associated with in‐hospital mortality for primary intracerebral hemorrhage (adjusted odd ratio 0.78, 95% CI 0.61–1.01), but reduced the proportion of patients undergoing evacuation of intracranial hematoma (adjusted odd ratio 0.70, 95% CI 0.61–0.82). Propensity score matching analyses yielded similar results. CONCLUSION: Prior statin use was not associated with in‐hospital mortality but did reduce evacuation of intracranial hematoma rates.