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Impact of cancer evolution on immune surveillance and checkpoint inhibitor response

Intratumour heterogeneity (ITH) is pervasive across all cancers studied and may provide the evolving tumour multiple routes to escape immune surveillance. Immune checkpoint inhibitors (CPIs) are rapidly becoming standard of care for many cancers. Here, we discuss recent work investigating the influe...

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Detalles Bibliográficos
Autores principales: Wu, Yin, Biswas, Dhruva, Swanton, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253787/
https://www.ncbi.nlm.nih.gov/pubmed/33631295
http://dx.doi.org/10.1016/j.semcancer.2021.02.013