Cryptococcus neoformans–Specific and Non–Cryptococcus neoformans–Specific Antibody Profiles in Organ Transplant Recipients With and Without Cryptococcosis

Antibody immunity has not been studied in organ transplant recipients (OTRs) with cryptococcosis. We determined serum antibody levels in OTRs: 23 cryptococcosis cases and 21 controls. Glucuronoxylomannan immunoglobulin M (IgM) and laminarin IgM were lower in cases than controls, were inversely assoc...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoon, Hyunah, Nakouzi, Antonio, Pappas, Peter G, Hemmige, Vagish S, Pirofski, Liise anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253883/
https://www.ncbi.nlm.nih.gov/pubmed/35794949
http://dx.doi.org/10.1093/ofid/ofac211
_version_ 1784740588100255744
author Yoon, Hyunah
Nakouzi, Antonio
Pappas, Peter G
Hemmige, Vagish S
Pirofski, Liise anne
author_facet Yoon, Hyunah
Nakouzi, Antonio
Pappas, Peter G
Hemmige, Vagish S
Pirofski, Liise anne
author_sort Yoon, Hyunah
collection PubMed
description Antibody immunity has not been studied in organ transplant recipients (OTRs) with cryptococcosis. We determined serum antibody levels in OTRs: 23 cryptococcosis cases and 21 controls. Glucuronoxylomannan immunoglobulin M (IgM) and laminarin IgM were lower in cases than controls, were inversely associated with cryptococcosis status, and may hold promise as markers of cryptococcosis.
format Online
Article
Text
id pubmed-9253883
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-92538832022-07-05 Cryptococcus neoformans–Specific and Non–Cryptococcus neoformans–Specific Antibody Profiles in Organ Transplant Recipients With and Without Cryptococcosis Yoon, Hyunah Nakouzi, Antonio Pappas, Peter G Hemmige, Vagish S Pirofski, Liise anne Open Forum Infect Dis Brief Report Antibody immunity has not been studied in organ transplant recipients (OTRs) with cryptococcosis. We determined serum antibody levels in OTRs: 23 cryptococcosis cases and 21 controls. Glucuronoxylomannan immunoglobulin M (IgM) and laminarin IgM were lower in cases than controls, were inversely associated with cryptococcosis status, and may hold promise as markers of cryptococcosis. Oxford University Press 2022-04-20 /pmc/articles/PMC9253883/ /pubmed/35794949 http://dx.doi.org/10.1093/ofid/ofac211 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Yoon, Hyunah
Nakouzi, Antonio
Pappas, Peter G
Hemmige, Vagish S
Pirofski, Liise anne
Cryptococcus neoformans–Specific and Non–Cryptococcus neoformans–Specific Antibody Profiles in Organ Transplant Recipients With and Without Cryptococcosis
title Cryptococcus neoformans–Specific and Non–Cryptococcus neoformans–Specific Antibody Profiles in Organ Transplant Recipients With and Without Cryptococcosis
title_full Cryptococcus neoformans–Specific and Non–Cryptococcus neoformans–Specific Antibody Profiles in Organ Transplant Recipients With and Without Cryptococcosis
title_fullStr Cryptococcus neoformans–Specific and Non–Cryptococcus neoformans–Specific Antibody Profiles in Organ Transplant Recipients With and Without Cryptococcosis
title_full_unstemmed Cryptococcus neoformans–Specific and Non–Cryptococcus neoformans–Specific Antibody Profiles in Organ Transplant Recipients With and Without Cryptococcosis
title_short Cryptococcus neoformans–Specific and Non–Cryptococcus neoformans–Specific Antibody Profiles in Organ Transplant Recipients With and Without Cryptococcosis
title_sort cryptococcus neoformans–specific and non–cryptococcus neoformans–specific antibody profiles in organ transplant recipients with and without cryptococcosis
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253883/
https://www.ncbi.nlm.nih.gov/pubmed/35794949
http://dx.doi.org/10.1093/ofid/ofac211
work_keys_str_mv AT yoonhyunah cryptococcusneoformansspecificandnoncryptococcusneoformansspecificantibodyprofilesinorgantransplantrecipientswithandwithoutcryptococcosis
AT nakouziantonio cryptococcusneoformansspecificandnoncryptococcusneoformansspecificantibodyprofilesinorgantransplantrecipientswithandwithoutcryptococcosis
AT pappaspeterg cryptococcusneoformansspecificandnoncryptococcusneoformansspecificantibodyprofilesinorgantransplantrecipientswithandwithoutcryptococcosis
AT hemmigevagishs cryptococcusneoformansspecificandnoncryptococcusneoformansspecificantibodyprofilesinorgantransplantrecipientswithandwithoutcryptococcosis
AT pirofskiliiseanne cryptococcusneoformansspecificandnoncryptococcusneoformansspecificantibodyprofilesinorgantransplantrecipientswithandwithoutcryptococcosis

Ejemplares similares