The Toxoplasma glucan phosphatase TgLaforin utilizes a distinct functional mechanism that can be exploited by therapeutic inhibitors

Toxoplasma gondii is an intracellular parasite that generates amylopectin granules (AGs), a polysaccharide associated with bradyzoites that define chronic T. gondii infection. AGs are postulated to act as an essential energy storage molecule that enable bradyzoite persistence, transmission, and reac...

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Detalles Bibliográficos
Autores principales: Murphy, Robert D., Chen, Tiantian, Lin, Jianping, He, Rongjun, Wu, Li, Pearson, Caden R., Sharma, Savita, Vander Kooi, Carl D., Sinai, Anthony P., Zhang, Zhong-Yin, Vander Kooi, Craig W., Gentry, Matthew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254107/
https://www.ncbi.nlm.nih.gov/pubmed/35640720
http://dx.doi.org/10.1016/j.jbc.2022.102089

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