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Unusual presentation of a small cell lung cancer with bilateral breast metastases: Case report and a brief review of the literature

Small cell lung cancer (SCLC) is a smoker's disease and occurs almost exclusively in smokers. SCLC is a high-grade neuroendocrine tumor and commonly presents as a central tumor with bulky mediastinal adenopathy. It is notorious for causing widespread disease and paraneoplastic syndromes. The us...

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Detalles Bibliográficos
Autores principales: Bannon, Mark, Marak, Creticus, Ashraf, Adrita, Smith, Chelsea, Nunley, Matthew, Guddati, Achuta Kumar, Kaushik, Prashant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254160/
https://www.ncbi.nlm.nih.gov/pubmed/35799863
http://dx.doi.org/10.1016/j.rmcr.2022.101693
Descripción
Sumario:Small cell lung cancer (SCLC) is a smoker's disease and occurs almost exclusively in smokers. SCLC is a high-grade neuroendocrine tumor and commonly presents as a central tumor with bulky mediastinal adenopathy. It is notorious for causing widespread disease and paraneoplastic syndromes. The usual sites of metastasis include the liver, brain, bone, and adrenals. SCLC presenting with breast metastasis is unusual; however, there are reports of unilateral and bilateral breast metastases. SCLC with bilateral breast metastases is extremely rare, with only five previously reported cases available in the literature. We are taking this opportunity to report and add to the growing literature on the unusual presentation of a small cell lung cancer with bilateral breast metastases.