Promising alternatives of CD47 monoclonal antibody: an injectable degradable hydrogel loaded with PQ912 for postoperative immunotherapy effectively blocks CD47-SIRPα signal

Rationale: Many cancers have evolved different mechanisms to evade immune surveillance. Macrophages, the innate defense of the immune system, are limited in their phagocytosis by CD47 anti-phagocytic signaling expressed on the surface of tumor cells. Although the CD47 monoclonal antibody (aCD47) str...

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Detalles Bibliográficos
Autores principales: Li, Chang, Liu, Yubo, Li, Dan, Wang, Qiu, Zhou, Shuang, Zhang, Haotian, Wang, Yongjun, He, Zhonggui, Liu, Hongzhuo, Sun, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254232/
https://www.ncbi.nlm.nih.gov/pubmed/35832081
http://dx.doi.org/10.7150/thno.72310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254232/
https://www.ncbi.nlm.nih.gov/pubmed/35832081
http://dx.doi.org/10.7150/thno.72310

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