FGFR blockade boosts T cell infiltration into triple-negative breast cancer by regulating cancer-associated fibroblasts

Background: Since T cell exclusion contributes to tumor immune evasion and immunotherapy resistance, how to improve T cell infiltration into solid tumors becomes an urgent challenge. Methods: We employed deep learning to profile the tumor immune microenvironment (TIME) in triple negative breast canc...

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Detalles Bibliográficos
Autores principales: Wu, Yushen, Yi, Ziying, Li, Jie, Wei, Yuxian, Feng, Rui, Liu, Jiazhou, Huang, Jiefeng, Chen, Yuru, Wang, Xiaoyu, Sun, Jiazheng, Yin, Xuedong, Li, Yunhai, Wan, Jingyuan, Zhang, Li, Huang, Jing, Du, Huimin, Wang, Xiaoyi, Li, Qin, Ren, Guosheng, Li, Hongzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254240/
https://www.ncbi.nlm.nih.gov/pubmed/35832090
http://dx.doi.org/10.7150/thno.68972

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