Plasma contains ultrashort single-stranded DNA in addition to nucleosomal cell-free DNA

Plasma cell-free DNA is being widely explored as a biomarker for clinical screening. Currently, methods are optimized for the extraction and detection of double-stranded mononucleosomal cell-free DNA of ∼160bp in length. We introduce uscfDNA-seq, a single-stranded cell-free DNA next-generation seque...

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Detalles Bibliográficos
Autores principales: Cheng, Jordan, Morselli, Marco, Huang, Wei-Lun, Heo, You Jeong, Pinheiro-Ferreira, Thalyta, Li, Feng, Wei, Fang, Chia, David, Kim, Yong, He, Hua-Jun, Cole, Kenneth D., Su, Wu-Chou, Pellegrini, Matteo, Wong, David T.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254344/
https://www.ncbi.nlm.nih.gov/pubmed/35800774
http://dx.doi.org/10.1016/j.isci.2022.104554

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