Cargando…

mTOR Inhibitor Use Is Associated With a Favorable Outcome of COVID-19 in Patients of Kidney Transplant: Results of a Retrospective Study

INTRODUCTION: In solid organ transplant recipients, COVID-19 is associated with a poor prognosis because of immunosuppression. Some studies suggest a potential therapeutic role of mammalian Target of Rapamycin (mTOR) inhibitors in SARS-CoV-2 infection. This study aimed to assess the impact of mTOR e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pinchera, Biagio, Spirito, Lorenzo, Buonomo, Antonio Riccardo, Foggia, Maria, Carrano, Rosa, Salemi, Fabrizio, Schettino, Elisa, Papa, Fortuna, La Rocca, Roberto, Crocetto, Felice, Napolitano, Luigi, Villari, Riccardo, Gentile, Ivan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254357/ https://www.ncbi.nlm.nih.gov/pubmed/35801204 http://dx.doi.org/10.3389/fmed.2022.852973

Ejemplares similares

SARS-CoV-2 in Kidney Transplant Patients: A Real-Life Experience
por: Pinchera, Biagio, et al.
Publicado: (2022)

Diabetes and COVID-19: The potential role of mTOR
por: Pinchera, B., et al.
Publicado: (2022)

Serological Response and Clinical Protection of Anti-SARS-CoV-2 Vaccination and the Role of Immunosuppressive Drugs in a Cohort of Kidney Transplant Patients
por: Biagio, Pinchera, et al.
Publicado: (2022)

Remdesivir Alone or in Combination with Monoclonal Antibodies as an Early Treatment to Prevent Severe COVID-19 in Patients with Mild/Moderate Disease at High Risk of Progression: A Single Centre, Real-Life Study
por: Scotto, Riccardo, et al.
Publicado: (2023)

Update on the Management of Surgical Site Infections
por: Pinchera, Biagio, et al.
Publicado: (2022)

Casirivimab/imdevimab + remdesivir in hospitalized patients with severe Covid-19: A single centre experience
por: Moriello, Nicola Schiano, et al.
Publicado: (2023)

Diabetes and SARS-CoV-2 Infection: The Potential Role of Antidiabetic Therapy in the Evolution of COVID-19
por: Pinchera, Biagio, et al.
Publicado: (2023)

A Simple Non-Invasive Score Based on Baseline Parameters Can Predict Outcome in Patients with COVID-19
por: Scotto, Riccardo, et al.
Publicado: (2022)

Nirmatrelvir/Ritonavir and Molnupiravir in the Treatment of Mild/Moderate COVID-19: Results of a Real-Life Study
por: Gentile, Ivan, et al.
Publicado: (2022)

Effect of Direct Antiviral Therapy Against HCV on CD4+ T Cell Count in Patients with HIV-HCV Coinfection
por: Pinchera, Biagio, et al.
Publicado: (2023)

Current evidence on the management of hepatitis B in pregnancy
por: Maraolo, Alberto Enrico, et al.
Publicado: (2018)

Monoclonal Antibodies against SARS-CoV-2 Infection: Results from a Real-Life Study before the Omicron Surge
por: Scotto, Riccardo, et al.
Publicado: (2022)

Pneumocystis jirovecii Pneumonia in Non-HIV Patients Recovering from COVID-19: A Single-Center Experience
por: Gentile, Ivan, et al.
Publicado: (2021)

Risk Factors for Pneumocystis jirovecii Pneumonia in Non-HIV Patients Hospitalized for COVID-19: A Case-Control Study
por: Viceconte, Giulio, et al.
Publicado: (2023)

The COVID-19 Pandemic: Is It A Wolf Consuming Fertility?
por: Napolitano, Luigi, et al.
Publicado: (2020)

The role of mTOR pathway as target for treatment in adrenocortical cancer
por: De Martino, Maria Cristina, et al.
Publicado: (2019)

Phosphorylated Mammalian Target of Rapamycin p-mTOR Is a Favorable Prognostic Factor than mTOR in Gastric Cancer
por: Cao, Guo-dong, et al.
Publicado: (2016)

COVID-19 Post-Exposure Evaluation (COPE) Study: Assessing the Role of Socio-Economic Factors in Household SARS-CoV-2 Transmission within Campania Region (Southern Italy)
por: Gentile, Ivan, et al.
Publicado: (2022)

mTOR favors senescence over quiescence in p53-arrested cells
por: Schug, Thaddeus T.
Publicado: (2010)

Nasopharyngeal Microbiome Signature in COVID-19 Positive Patients: Can We Definitively Get a Role to Fusobacterium periodonticum?
por: Nardelli, Carmela, et al.
Publicado: (2021)

mTOR pathway activation is a favorable prognostic factor in human prostate adenocarcinoma
por: Stelloo, Suzan, et al.
Publicado: (2016)

mTOR inhibitors activate PERK signaling and favor viability of gastrointestinal neuroendocrine cell lines
por: Freis, Patricia, et al.
Publicado: (2017)

Low temperature and mTOR inhibition favor stem cell maintenance in human keratinocyte cultures
por: Nanba, Daisuke, et al.
Publicado: (2023)

Cytoreductive Nephrectomy and Metastatic Renal Cell Carcinoma: State of the Art and Future Perspectives
por: Napolitano, Luigi, et al.
Publicado: (2023)

No Detection of SARS-CoV-2 RNA on Urethral Swab in Patients with Positive Nasopharyngeal Swab
por: Spirito, Lorenzo, et al.
Publicado: (2020)

Gastrointestinal tract diseases as a risk factor for SARSCoV2 rectal shedding? An Italian report on 10 COVID-19 patients
por: Patrì, Angela, et al.
Publicado: (2021)

Case Report: Discovery a Novel SARS-CoV-2 Variant in a Six-Months Long-Term Swab Positive Female Suffering From Non-Hodgkin Lymphoma
por: Capoluongo, Ettore, et al.
Publicado: (2021)

Overcoming mTOR Resistance Mutations with a New Generation mTOR Inhibitor
por: Rodrik-Outmezguine, Vanessa S., et al.
Publicado: (2016)

mTOR Pathway and mTOR Inhibitors in Head and Neck Cancer
por: Gao, Wei, et al.
Publicado: (2012)

Myelination and mTOR
por: Figlia, Gianluca, et al.
Publicado: (2017)

Pml represses tumour progression through inhibition of mTOR
por: Bernardi, Rosa, et al.
Publicado: (2011)

mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges
por: Zou, Zhilin, et al.
Publicado: (2020)

BNT162b2 Elicited an Efficient Cell-Mediated Response against SARS-CoV-2 in Kidney Transplant Recipients and Common Variable Immunodeficiency Patients
por: La Civita, Evelina, et al.
Publicado: (2023)

Mammalian Target of Rapamycin (mTOR) Signaling at the Crossroad of Muscle Fiber Fate in Sarcopenia
por: Sirago, Giuseppe, et al.
Publicado: (2022)

mTOR Signaling in Cancer and mTOR Inhibitors in Solid Tumor Targeting Therapy
por: Tian, Tian, et al.
Publicado: (2019)

Regulation of Osteoclast Growth and Fusion by mTOR/raptor and mTOR/rictor/Akt
por: Tiedemann, Kerstin, et al.
Publicado: (2017)

Escaping mTOR inhibition for cancer therapy: Tumor suppressor functions of mTOR
por: Villar, Victor H., et al.
Publicado: (2017)

mTOR-dependent phosphorylation controls TFEB nuclear export
por: Napolitano, Gennaro, et al.
Publicado: (2018)

The Role of mTOR in Neuroendocrine Tumors: Future Cornerstone of a Winning Strategy?
por: Lamberti, Giuseppe, et al.
Publicado: (2018)

mTOR and lysosome regulation
por: Puertollano, Rosa
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_l3k8t1efct2kgg2tk7s1vcrhu6