Myasthenia gravis with ocular symptoms following a ChAdOx1 nCoV-19 vaccination: A case report

PURPOSE: We report on the case of a 35-year-old man who developed myasthenia gravis with ocular symptoms following a ChAdOx1 nCoV-19 vaccine injection. OBSERVATIONS: A 35-year-old man complained of binocular diplopia one month following ChAdOx1 nCoV-19 vaccination. He had weak infraduction of the le...

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Detalles Bibliográficos
Autores principales: Kang, Min Chae, Park, Kyung-Ah, Min, Ju-Hong, Oh, Sei Yeul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254405/
https://www.ncbi.nlm.nih.gov/pubmed/35800401
http://dx.doi.org/10.1016/j.ajoc.2022.101620
Descripción
Sumario:PURPOSE: We report on the case of a 35-year-old man who developed myasthenia gravis with ocular symptoms following a ChAdOx1 nCoV-19 vaccine injection. OBSERVATIONS: A 35-year-old man complained of binocular diplopia one month following ChAdOx1 nCoV-19 vaccination. He had weak infraduction of the left eye. Upper and lower extremity strength was normal on presentation. A serum antiacetylcholine receptor antibody titer was elevated at 1.60 nmol/L. His diplopia improved temporarily following the application of an ice pack for 2 min. CONCLUSIONS AND IMPORTANCE: This case report describes a rare occurrence of myasthenia gravis with ocular symptoms as a potential complication of ChAdOx1 nCoV-19 vaccination.

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