Insulin Directs Dichotomous Translational Regulation to Control Human Pluripotent Stem Cell Survival, Proliferation and Pluripotency

Insulin is essential for diverse biological processes in human pluripotent stem cells (hPSCs). However, the underlying mechanism of insulin's multitasking ability remains largely unknown. Here, we show that insulin controls hPSC survival and proliferation by modulating RNA translation via disti...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaoxiao, Ren, Zhili, Xu, Jiaqi, Deng, Chunhao, Zhang, Zhaoying, Godoy-Parejo, Carlos, Xu, Faxiang, Huang, Esther Chi Cheng, Wang, Jiajia, Cai, Zheyu, Liu, Weiwei, Hu, Guang, Chen, Guokai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254461/
https://www.ncbi.nlm.nih.gov/pubmed/35813470
http://dx.doi.org/10.7150/ijbs.71199

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