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NUF2 Drives Clear Cell Renal Cell Carcinoma by Activating HMGA2 Transcription through KDM2A-mediated H3K36me2 Demethylation

The poor sensitivity of clear cell renal cell carcinoma (ccRCC) to conventional chemotherapy and radiotherapy makes its treatment challenging. The Ndc80 kinetochore complex component (NUF2) is involved in the development and progression of several cancers. However, its role in ccRCC remains unclear....

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Detalles Bibliográficos
Autores principales:	Lin, Jiatian, Chen, Xiangling, Yu, Hongjian, Min, Shasha, Chen, Yequn, Li, Zesong, Xie, Xina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254462/ https://www.ncbi.nlm.nih.gov/pubmed/35813477 http://dx.doi.org/10.7150/ijbs.70972

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