Egr1 confers protection against acetaminophen‑induced hepatotoxicity via transcriptional upregulating of Acaa2

Background: Acetaminophen (APAP)-induced liver injury (AILI) is a common cause of drug-induced liver injury (DILI). The mechanism underlying protection in AILI or DILI remains to be elucidated, and the role of early growth response 1 (Egr1) in AILI and potential mechanisms remain to be known. Method...

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Detalles Bibliográficos
Autores principales: Lei, Xiaohong, Xu, Qingling, Li, Chunmin, Niu, Baolin, Ming, Yanan, Li, Jing, Tang, Yingyue, Li, Xiaoyun, Tang, Jieting, Wu, Jing, Ju, Yi, Yao, Lvfeng, Wang, Bin, Miao, Qi, Zhong, Wei, Zhi, Yang, Xu, Lirong, Li, Chaojun, Li, Xiaobo, Mao, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254463/
https://www.ncbi.nlm.nih.gov/pubmed/35813467
http://dx.doi.org/10.7150/ijbs.71781

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