Hypoxia-inducible CircPFKFB4 Promotes Breast Cancer Progression by Facilitating the CRL4(DDB2) E3 Ubiquitin Ligase-mediated p27 Degradation

Hypoxic microenvironment and circular RNAs (circRNAs) have shown critical implications in breast cancer (BC) progression. However, the specific functions and underlying mechanisms of circRNAs in BC under hypoxia remain largely unknown. We first screened for differentially expressed circRNAs in normo...

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Detalles Bibliográficos
Autores principales: Chen, Hang, Yang, Rui, Xing, Lei, Wang, Bin, Liu, Dawei, Ou, Xiaoqiang, Deng, Yumei, Jiang, Rong, Chen, Junxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254479/
https://www.ncbi.nlm.nih.gov/pubmed/35813480
http://dx.doi.org/10.7150/ijbs.72842

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