Suppressor mutations in Escherichia coli RNA polymerase alter transcription initiation but do not affect translesion RNA synthesis in vitro

Bacterial RNA polymerase (RNAP) coordinates transcription with DNA repair and replication. Many RNAP mutations have pleiotropic phenotypes with profound effects on transcription-coupled processes. One class of RNAP mutations (rpo∗) has been shown to suppress mutations in regulatory factors responsib...

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Detalles Bibliográficos
Autores principales: Miropolskaya, Nataliya, Petushkov, Ivan, Esyunina, Daria, Kulbachinskiy, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254596/
https://www.ncbi.nlm.nih.gov/pubmed/35667439
http://dx.doi.org/10.1016/j.jbc.2022.102099

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