Pycard and BC017158 Candidate Genes of Irm1 Locus Modulate Inflammasome Activation for IL-1β Production

We identified Pycard and BC017158 genes as putative effectors of the Quantitative Trait locus (QTL) that we mapped at distal chromosome 7 named Irm1 for Inflammatory response modulator 1, controlling acute inflammatory response (AIR) and the production of IL-1β, dependent on the activation of the NL...

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Detalles Bibliográficos
Autores principales: Borrego, Andrea, Colombo, Francesca, de Souza, Jean Gabriel, Jensen, José Ricardo, Dassano, Alice, Piazza, Rocco, Rodrigues dos Santos, Barbara Anaís, Ribeiro, Orlando Garcia, De Franco, Marcelo, Cabrera, Wafa Hanna Koury, Icimoto, Marcelo Yudi, Starobinas, Nancy, Magalhães, Geraldo, Monteleone, Leticia Figueiredo, Eto, Silas Fernandes, DeOcesano-Pereira, Carlos, Goldfeder, Mauricio Barbugiani, Pasqualoto, Kerly Fernanda Mesquita, Dragani, Tommaso A., Ibañez, Olga Célia Martinez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254735/
https://www.ncbi.nlm.nih.gov/pubmed/35799794
http://dx.doi.org/10.3389/fimmu.2022.899569

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