Separating clinical antibodies from repertoire antibodies, a path to in silico developability assessment

Approaches for antibody discovery have seen substantial improvement and success in recent years. Yet, advancing antibodies into the clinic remains difficult because therapeutic developability concerns are challenging to predict. We developed a computational model to simplify antibody developability...

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Detalles Bibliográficos
Autores principales: Negron, Christopher, Fang, Joyce, McPherson, Michael J., Stine, W. Blaine, McCluskey, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255221/
https://www.ncbi.nlm.nih.gov/pubmed/35771588
http://dx.doi.org/10.1080/19420862.2022.2080628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255221/
https://www.ncbi.nlm.nih.gov/pubmed/35771588
http://dx.doi.org/10.1080/19420862.2022.2080628

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