Oncolytic adenovirus promotes vascular normalization and nonclassical tertiary lymphoid structure formation through STING-mediated DC activation

Inducing a full antitumor immune response in the tumor microenvironment (TME) is essential for successful cancer immunotherapy. Here, we report that an oncolytic adenovirus carrying mIL-15 (Ad-IL15) can effectively induce antitumor immune response and inhibit tumor growth in a mouse model of cancer....

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Detalles Bibliográficos
Autores principales: He, Teng, Hao, Zhixing, Lin, Mingjie, Xin, Zhongwei, Chen, Yongyuan, Ouyang, Wei, Yang, Qi, Chen, Xiaoke, Zhou, Hui, Zhang, Wanying, Wu, Pin, Xu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255224/
https://www.ncbi.nlm.nih.gov/pubmed/35800155
http://dx.doi.org/10.1080/2162402X.2022.2093054

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