Downregulation of SATB1 by miRNAs reduces megakaryocyte/erythroid progenitor expansion in preclinical models of Diamond–Blackfan anemia

Diamond−Blackfan Anemia (DBA) is an inherited bone marrow failure syndrome that is associated with anemia, congenital anomalies, and cancer predisposition. It is categorized as a ribosomopathy, because more than 80% or patients have haploinsufficiency of either a small or large subunit-associated ri...

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Detalles Bibliográficos
Autores principales: Wilkes, Mark C., Scanlon, Vanessa, Shibuya, Aya, Cepika, Alma-Martina, Eskin, Ascia, Chen, Zugen, Narla, Anupama, Glader, Bert, Roncarolo, Maria Grazia, Nelson, Stanley F., Sakamoto, Kathleen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255422/
https://www.ncbi.nlm.nih.gov/pubmed/35460833
http://dx.doi.org/10.1016/j.exphem.2022.04.005

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