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Trends, Advantages and Disadvantages in Combined Extracorporeal Lung and Kidney Support From a Technical Point of View
Extracorporeal membrane oxygenation (ECMO) provides pulmonary and/or cardiac support for critically ill patients. Due to their diseases, they are at high risk of developing acute kidney injury. In that case, continuous renal replacement therapy (CRRT) is applied to provide renal support and fluid ma...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255675/ https://www.ncbi.nlm.nih.gov/pubmed/35800469 http://dx.doi.org/10.3389/fmedt.2022.909990 |
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author | Martins Costa, Ana Halfwerk, Frank Wiegmann, Bettina Neidlin, Michael Arens, Jutta |
author_facet | Martins Costa, Ana Halfwerk, Frank Wiegmann, Bettina Neidlin, Michael Arens, Jutta |
author_sort | Martins Costa, Ana |
collection | PubMed |
description | Extracorporeal membrane oxygenation (ECMO) provides pulmonary and/or cardiac support for critically ill patients. Due to their diseases, they are at high risk of developing acute kidney injury. In that case, continuous renal replacement therapy (CRRT) is applied to provide renal support and fluid management. The ECMO and CRRT circuits can be combined by an integrated or parallel approach. So far, all methods used for combined extracorporeal lung and kidney support present serious drawbacks. This includes not only high risks of circuit related complications such as bleeding, thrombus formation, and hemolysis, but also increase in technical workload and health care costs. In this sense, the development of a novel optimized artificial lung device with integrated renal support could offer important treatment benefits. Therefore, we conducted a review to provide technical background on existing techniques for extracorporeal lung and kidney support and give insight on important aspects to be addressed in the development of this novel highly integrated artificial lung device. |
format | Online Article Text |
id | pubmed-9255675 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-92556752022-07-06 Trends, Advantages and Disadvantages in Combined Extracorporeal Lung and Kidney Support From a Technical Point of View Martins Costa, Ana Halfwerk, Frank Wiegmann, Bettina Neidlin, Michael Arens, Jutta Front Med Technol Medical Technology Extracorporeal membrane oxygenation (ECMO) provides pulmonary and/or cardiac support for critically ill patients. Due to their diseases, they are at high risk of developing acute kidney injury. In that case, continuous renal replacement therapy (CRRT) is applied to provide renal support and fluid management. The ECMO and CRRT circuits can be combined by an integrated or parallel approach. So far, all methods used for combined extracorporeal lung and kidney support present serious drawbacks. This includes not only high risks of circuit related complications such as bleeding, thrombus formation, and hemolysis, but also increase in technical workload and health care costs. In this sense, the development of a novel optimized artificial lung device with integrated renal support could offer important treatment benefits. Therefore, we conducted a review to provide technical background on existing techniques for extracorporeal lung and kidney support and give insight on important aspects to be addressed in the development of this novel highly integrated artificial lung device. Frontiers Media S.A. 2022-06-21 /pmc/articles/PMC9255675/ /pubmed/35800469 http://dx.doi.org/10.3389/fmedt.2022.909990 Text en Copyright © 2022 Martins Costa, Halfwerk, Wiegmann, Neidlin and Arens. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Medical Technology Martins Costa, Ana Halfwerk, Frank Wiegmann, Bettina Neidlin, Michael Arens, Jutta Trends, Advantages and Disadvantages in Combined Extracorporeal Lung and Kidney Support From a Technical Point of View |
title | Trends, Advantages and Disadvantages in Combined Extracorporeal Lung and Kidney Support From a Technical Point of View |
title_full | Trends, Advantages and Disadvantages in Combined Extracorporeal Lung and Kidney Support From a Technical Point of View |
title_fullStr | Trends, Advantages and Disadvantages in Combined Extracorporeal Lung and Kidney Support From a Technical Point of View |
title_full_unstemmed | Trends, Advantages and Disadvantages in Combined Extracorporeal Lung and Kidney Support From a Technical Point of View |
title_short | Trends, Advantages and Disadvantages in Combined Extracorporeal Lung and Kidney Support From a Technical Point of View |
title_sort | trends, advantages and disadvantages in combined extracorporeal lung and kidney support from a technical point of view |
topic | Medical Technology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255675/ https://www.ncbi.nlm.nih.gov/pubmed/35800469 http://dx.doi.org/10.3389/fmedt.2022.909990 |
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