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Selfish centromeres and the wastefulness of human reproduction
Many human embryos die in utero owing to an excess or deficit of chromosomes, a phenomenon known as aneuploidy; this is largely a consequence of nondisjunction during maternal meiosis I. Asymmetries of this division render it vulnerable to selfish centromeres that promote their own transmission, the...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255743/ https://www.ncbi.nlm.nih.gov/pubmed/35788750 http://dx.doi.org/10.1371/journal.pbio.3001671 |