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Transdermal delivery of interleukin-12 gene targeting dendritic cells enhances the anti-tumour effect of programmed cell death protein 1 monoclonal antibody

Recent studies have suggested that the anti-tumour effect of the programmed cell death protein 1 monoclonal antibody (aPD-1) depends on the expression of interleukin-12 (IL-12) by dendritic cells (DCs). Since DCs are abundant in skin tissues, transdermal delivery of IL-12 targeting DCs may significa...

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Detalles Bibliográficos
Autores principales:	Hong, Huoyan, Wang, Xiaoyun, Song, Xinran, Fawal, Gomaa El, Wang, Kaili, Jiang, Di, Pei, Yifei, Wang, Zhe, Wang, Hongsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Chinese Medical Multimedia Press Co., Ltd 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255785/ https://www.ncbi.nlm.nih.gov/pubmed/35836967 http://dx.doi.org/10.12336/biomatertransl.2021.02.005

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