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Human and mouse muscle transcriptomic analyses identify insulin receptor mRNA downregulation in hyperinsulinemia‐associated insulin resistance

Hyperinsulinemia is commonly viewed as a compensatory response to insulin resistance, yet studies have demonstrated that chronically elevated insulin may also drive insulin resistance. The molecular mechanisms underpinning this potentially cyclic process remain poorly defined, especially on a transc...

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Detalles Bibliográficos
Autores principales:	Cen, Haoning Howard, Hussein, Bahira, Botezelli, José Diego, Wang, Su, Zhang, Jiashuo Aaron, Noursadeghi, Nilou, Jessen, Niels, Rodrigues, Brian, Timmons, James A., Johnson, James D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255858/ https://www.ncbi.nlm.nih.gov/pubmed/34921686 http://dx.doi.org/10.1096/fj.202100497RR

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