Cargando…
Continuous treatment with abemaciclib leads to sustained and efficient inhibition of breast cancer cell proliferation
Abemaciclib is an oral, selective cyclin-dependent kinase 4 & 6 inhibitor (CDK4 & 6i), approved for hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2–) advanced breast cancer (ABC) as monotherapy for endocrine refractory disease, and with endocrine ther...
Autores principales: | Torres-Guzmán, Raquel, Ganado, Maria Patricia, Mur, Cecilia, Marugan, Carlos, Baquero, Carmen, Yang, Yanzhu, Zeng, Yi, Bian, Huimin, Du, Jian, de Dios, Alfonso, Puig, Oscar, Lallena, María José |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255995/ https://www.ncbi.nlm.nih.gov/pubmed/35813283 http://dx.doi.org/10.18632/oncotarget.28249 |
Ejemplares similares
-
Crystal structure of active CDK4-cyclin D and mechanistic basis for abemaciclib efficacy
por: Gharbi, Severine Isabelle, et al.
Publicado: (2022) -
Author Correction: Crystal structure of active CDK4-cyclin D and mechanistic basis for abemaciclib efficacy
por: Gharbi, Severine Isabelle, et al.
Publicado: (2022) -
Preclinical characterization of abemaciclib in hormone receptor positive breast cancer
por: Torres-Guzmán, Raquel, et al.
Publicado: (2017) -
Phenotypic Screening Approaches to Develop Aurora Kinase Inhibitors: Drug Discovery Perspectives
por: Marugán, Carlos, et al.
Publicado: (2016) -
Clinical Management of Potential Toxicity of Abemaciclib and Approaches to Ensure Treatment Continuation
por: Takada, Shinya, et al.
Publicado: (2023)