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The Prognostic Value of TP53 Alteration in Patients with Head and Neck Squamous Cell Carcinoma Receiving Immunotherapy

The article by Wilson et al., published in the February 2021 issue, reported the prognostic value of circulating tumor DNA (ctDNA) sequencing in head and neck squamous cell carcinoma (HNSCC), noting TP53 as the most altered and concordant gene in ctDNA and tDNA. This Letter to the Editor further con...

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Autores principales: Jiang, Chao, Zhou, Xuanchen, Han, Jie, Yue, Zhiyong, Li, Butuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256032/
https://www.ncbi.nlm.nih.gov/pubmed/35536754
http://dx.doi.org/10.1093/oncolo/oyac087
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author Jiang, Chao
Zhou, Xuanchen
Han, Jie
Yue, Zhiyong
Li, Butuo
author_facet Jiang, Chao
Zhou, Xuanchen
Han, Jie
Yue, Zhiyong
Li, Butuo
author_sort Jiang, Chao
collection PubMed
description The article by Wilson et al., published in the February 2021 issue, reported the prognostic value of circulating tumor DNA (ctDNA) sequencing in head and neck squamous cell carcinoma (HNSCC), noting TP53 as the most altered and concordant gene in ctDNA and tDNA. This Letter to the Editor further considers the role of TP53 alteration in the prognosis prediction of immunotherapy in HNSCC.
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spelling pubmed-92560322022-07-06 The Prognostic Value of TP53 Alteration in Patients with Head and Neck Squamous Cell Carcinoma Receiving Immunotherapy Jiang, Chao Zhou, Xuanchen Han, Jie Yue, Zhiyong Li, Butuo Oncologist Letters to the Editor The article by Wilson et al., published in the February 2021 issue, reported the prognostic value of circulating tumor DNA (ctDNA) sequencing in head and neck squamous cell carcinoma (HNSCC), noting TP53 as the most altered and concordant gene in ctDNA and tDNA. This Letter to the Editor further considers the role of TP53 alteration in the prognosis prediction of immunotherapy in HNSCC. Oxford University Press 2022-05-10 /pmc/articles/PMC9256032/ /pubmed/35536754 http://dx.doi.org/10.1093/oncolo/oyac087 Text en © The Author(s) 2022. Published by Oxford University Press. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Letters to the Editor
Jiang, Chao
Zhou, Xuanchen
Han, Jie
Yue, Zhiyong
Li, Butuo
The Prognostic Value of TP53 Alteration in Patients with Head and Neck Squamous Cell Carcinoma Receiving Immunotherapy
title The Prognostic Value of TP53 Alteration in Patients with Head and Neck Squamous Cell Carcinoma Receiving Immunotherapy
title_full The Prognostic Value of TP53 Alteration in Patients with Head and Neck Squamous Cell Carcinoma Receiving Immunotherapy
title_fullStr The Prognostic Value of TP53 Alteration in Patients with Head and Neck Squamous Cell Carcinoma Receiving Immunotherapy
title_full_unstemmed The Prognostic Value of TP53 Alteration in Patients with Head and Neck Squamous Cell Carcinoma Receiving Immunotherapy
title_short The Prognostic Value of TP53 Alteration in Patients with Head and Neck Squamous Cell Carcinoma Receiving Immunotherapy
title_sort prognostic value of tp53 alteration in patients with head and neck squamous cell carcinoma receiving immunotherapy
topic Letters to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256032/
https://www.ncbi.nlm.nih.gov/pubmed/35536754
http://dx.doi.org/10.1093/oncolo/oyac087
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