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Ruscogenin Ameliorated Sjögren's Syndrome by Inhibiting NLRP3 Inflammasome Activation

This article investigated the role and the specific mechanism of Ruscogenin in Sjögren's syndrome (SS). NOD/ShiLtJ mice were treated with Ruscogenin, and acinar cells isolated from submandibular glands were treated with TNF-α, Ruscogenin and transfected with NLRP3 overexpression plasmid. Saliva...

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Detalles Bibliográficos
Autores principales:	He, Jing, Wang, Yue, Xu, Lei, Xu, Changsong, Zhu, Yamei, Xu, Meimei, Chen, Yueyue, Guo, Liang, Hu, Wei, Xu, Dake, Jing, Rongyue, Xu, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256408/ https://www.ncbi.nlm.nih.gov/pubmed/35800007 http://dx.doi.org/10.1155/2022/6425121

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