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Long-Term Stability of Hydromorphone in Human Plasma Frozen at −20°C for Three Years Quantified by LC-MS/MS
The long-term stability of drugs under normal laboratory storage conditions (−20°C) for years is important for research purposes, clinical re-evaluation, and also for forensic toxicology. To evaluate the stability of the analgesic opioid hydromorphone, 44 human frozen plasma samples of a former clin...
Autores principales: | Wehrfritz, Andreas, Schmidt, Stefanie, Ihmsen, Harald, Schüttler, Jürgen, Jeleazcov, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256429/ https://www.ncbi.nlm.nih.gov/pubmed/35801191 http://dx.doi.org/10.1155/2022/3645048 |
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