Cargando…
Tangshenning Attenuates High Glucose-Induced Podocyte Injury via Restoring Autophagy Activity through Inhibiting mTORC1 Activation
Diabetic nephropathy (DN) is a microvascular complication of diabetes mellitus (DM) and the most common cause of death in diabetic patients. DN progression is associated with podocyte damage due to reduced autophagy caused by mTORC1 activation. Tangshenning (TSN) has been shown to reduce proteinuria...
Autores principales: | Xu, Jiayi, Shan, Xiaomeng, Chen, Chunwei, Gao, Yanbin, Zou, Dawei, Wang, Xiaolei, Wang, Tao, Shi, Yimin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256440/ https://www.ncbi.nlm.nih.gov/pubmed/35799948 http://dx.doi.org/10.1155/2022/1610416 |
Ejemplares similares
-
Ginsenoside Rg1 Alleviates Podocyte EMT Passage by Regulating AKT/GSK3 β/β-Catenin Pathway by Restoring Autophagic Activity
por: Shi, Yimin, et al.
Publicado: (2020) -
Glomerular mTORC1 activation was associated with podocytes to endothelial cells communication in lupus nephritis
por: Liu, Xiaotian, et al.
Publicado: (2023) -
Association of crumbs homolog-2 with mTORC1 in developing podocyte
por: Hamano, Sho, et al.
Publicado: (2018) -
Astragaloside IV inhibits glucose-induced epithelial-mesenchymal transition of podocytes through autophagy enhancement via the SIRT–NF-κB p65 axis
por: Wang, Xiaolei, et al.
Publicado: (2019) -
Regulation of Autophagy through TORC1 and mTORC1
por: Noda, Takeshi
Publicado: (2017)