Cargando…

LINC00092 Modulates Oxidative Stress and Glycolysis of Breast Cancer Cells via Pyruvate Carboxylase-Mediated AKT/mTOR Pathway

BACKGROUND: The discovery of noncoding RNAs (ncRNAs) offers new options for cancer-targeted therapy. This study is aimed at exploring the regulatory function of LINC00092 on breast cancer (BC) oxidative stress and glycolysis, along with internal mechanism concerning pyruvate carboxylase (PC). METHOD...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Wei, Liu, Yushan, Kang, Shaohong, Lv, Xinying, Fu, Wenfen, Zhang, Jie, Song, Chuangui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256459/ https://www.ncbi.nlm.nih.gov/pubmed/35799892 http://dx.doi.org/10.1155/2022/5215748

Ejemplares similares

LINC00941 promoted in vitro progression and glycolysis of laryngocarcinoma by upregulating PKM via activating the PI3K/AKT/mTOR signaling pathway
por: Li, Zhihai, et al.
Publicado: (2022)

Pyruvate carboxylase and cancer progression
por: Kiesel, Violet A., et al.
Publicado: (2021)

Glycolysis is suppressed by DCZ0801-induced inactivation of the Akt/mTOR pathway in Multiple Myeloma
por: Feng, Qilin, et al.
Publicado: (2020)

Deoxyshikonin Inhibits Viability and Glycolysis by Suppressing the Akt/mTOR Pathway in Acute Myeloid Leukemia Cells
por: Wu, Huijuan, et al.
Publicado: (2020)

ARHGAP25 Inhibits Pancreatic Adenocarcinoma Growth by Suppressing Glycolysis via AKT/mTOR Pathway
por: Huang, Wen-Kuan, et al.
Publicado: (2021)

The Paradox of Akt-mTOR Interactions
por: Vadlakonda, Lakshmipathi, et al.
Publicado: (2013)

Regulation of Osteoclast Growth and Fusion by mTOR/raptor and mTOR/rictor/Akt
por: Tiedemann, Kerstin, et al.
Publicado: (2017)

Lower expression of LINC00092 in lung adenocarcinoma might mean poorer prognosis: A study based on data mining and bioinformatics
por: Wang, Xin, et al.
Publicado: (2020)

Quercetin Inhibits the Proliferation of Glycolysis-Addicted HCC Cells by Reducing Hexokinase 2 and Akt-mTOR Pathway
por: Wu, Hongyan, et al.
Publicado: (2019)

A Unique Case of Pyruvate Carboxylase Deficiency
por: Hidalgo, Jessica, et al.
Publicado: (2021)

Targeting mTOR and Glycolysis in HER2-Positive Breast Cancer
por: Holloway, Ryan W., et al.
Publicado: (2021)

Linc01014 regulates gefitinib resistance in oesophagus cancer via EGFR‐PI3K‐AKT‐mTOR signalling pathway
por: Fu, Xiao, et al.
Publicado: (2019)

Expression of Pyruvate Carboxylase mRNA Variants in Liver of Dairy Cattle at Calving
por: Agca, Cansu, et al.
Publicado: (2007)

LINC00092 Suppresses the Malignant Progression of Breast Invasive Ductal Carcinoma Through Modulating SFRP1 Expression by Sponging miR-1827
por: Zhao, Chun-Ming, et al.
Publicado: (2022)

Pyruvate carboxylase deficiency: An underestimated cause of lactic acidosis
por: Habarou, F., et al.
Publicado: (2014)

Glycolysis-related biomarker TCIRG1 participates in regulation of renal cell carcinoma progression and tumor immune microenvironment by affecting aerobic glycolysis and AKT/mTOR signaling pathway
por: Di, Sichen, et al.
Publicado: (2023)

The PI3K-Akt-mTOR pathway mediates renal pericyte-myofibroblast transition by enhancing glycolysis through HKII
por: Chen, Liangmei, et al.
Publicado: (2023)

Akt and mTOR in B Cell Activation and Differentiation
por: Limon, Jose J., et al.
Publicado: (2012)

Akt and mTOR mediate programmed necrosis in neurons
por: Liu, Q, et al.
Publicado: (2014)

Mechanisms of Inhibition of Rhizobium etli Pyruvate Carboxylase by l-Aspartate
por: Sirithanakorn, Chaiyos, et al.
Publicado: (2014)

A distinct holoenzyme organization for two-subunit pyruvate carboxylase
por: Choi, Philip H., et al.
Publicado: (2016)

Allosteric regulation alters carrier domain translocation in pyruvate carboxylase
por: Liu, Yumeng, et al.
Publicado: (2018)

Pyruvate carboxylase supports the pulmonary tropism of metastatic breast cancer
por: Shinde, Aparna, et al.
Publicado: (2018)

Fibroblast pyruvate carboxylase is required for collagen production in the tumor microenvironment
por: Schwörer, Simon, et al.
Publicado: (2021)

The mTOR inhibitor AZD8055 inhibits proliferation and glycolysis in cervical cancer cells
por: LI, SHAORU, et al.
Publicado: (2013)

MLXIPL promotes the migration, invasion, and glycolysis of hepatocellular carcinoma cells by phosphorylation of mTOR
por: Chang, Xiaowei, et al.
Publicado: (2023)

Inhibition of the AKT/mTOR pathway negatively regulates PTEN expression via miRNAs: Effect of Akt/mTOR inhibition on PTEN expression
por: Wan, Linyan, et al.
Publicado: (2022)

USF1-ATRAP-PBX3 Axis Promote Breast Cancer Glycolysis and Malignant Phenotype by Activating AKT/mTOR Signaling
por: Wang, Dandan, et al.
Publicado: (2022)

The AKT/mTOR Signaling Pathway Was Mediated through the LINC00514/miR-28-5p/TRIM44 Axis
por: Wu, Lin, et al.
Publicado: (2022)

Knockdown of LINC01279 Suppresses Gastric Cancer Proliferation and Migration by Inhibiting PI3K/Akt/mTOR Signaling Pathway
por: Zhao, Weidong, et al.
Publicado: (2022)

PBRM1 deficiency oncogenic addiction is associated with activated AKT–mTOR signalling and aerobic glycolysis in clear cell renal cell carcinoma cells
por: Tang, Yu, et al.
Publicado: (2022)

PI3K/AKT/mTOR Pathway in Angiogenesis
por: Karar, Jayashree, et al.
Publicado: (2011)

Exclusive inhibition of PI3K/Akt/mTOR signaling is not sufficient to prevent PDGF-mediated effects on glycolysis and proliferation in colorectal cancer
por: Moench, Romana, et al.
Publicado: (2016)

Canagliflozin Modulates Hypoxia-Induced Metastasis, Angiogenesis and Glycolysis by Decreasing HIF-1α Protein Synthesis via AKT/mTOR Pathway
por: Luo, Jingyi, et al.
Publicado: (2021)

Receptor for activated C kinase 1 promotes cervical cancer lymph node metastasis via the glycolysis-dependent AKT/mTOR signaling
por: Xu, Lixiu, et al.
Publicado: (2022)

LncRNA LINC00998 inhibits the malignant glioma phenotype via the CBX3-mediated c-Met/Akt/mTOR axis
por: Cai, Haiping, et al.
Publicado: (2020)

The mTOR Pathway Regulates PKM2 to Affect Glycolysis in Esophageal Squamous Cell Carcinoma
por: Xiaoyu, He, et al.
Publicado: (2018)

Human herpesvirus 6A promotes glycolysis in infected T cells by activation of mTOR signaling
por: Wu, Zhisheng, et al.
Publicado: (2020)

Enhanced glycolysis in granulosa cells promotes the activation of primordial follicles through mTOR signaling
por: Zhang, Xiaodan, et al.
Publicado: (2022)

LINC01278 Induces Autophagy to Inhibit Tumour Progression by Suppressing the mTOR Signalling Pathway
por: Liu, Bo, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_6qodjiqrkptja0lfksp3t2gkk1