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CD146 increases stemness and aggressiveness in glioblastoma and activates YAP signaling
Glioblastoma (GBM), a highly malignant and lethal brain tumor, is characterized by diffuse invasion into the brain and chemo-radiotherapy resistance resulting in poor prognosis. In this study, we examined the involvement of the cell adhesion molecule CD146/MCAM in regulating GBM aggressiveness. Anal...
Autores principales: | Liang, Yuanke, Voshart, Daniëlle, Paridaen, Judith T. M. L., Oosterhof, Nynke, Liang, Dong, Thiruvalluvan, Arun, Zuhorn, Inge S., den Dunnen, Wilfred F. A., Zhang, Guojun, Lin, Haoyu, Barazzuol, Lara, Kruyt, Frank A. E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256581/ https://www.ncbi.nlm.nih.gov/pubmed/35790583 http://dx.doi.org/10.1007/s00018-022-04420-0 |
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