Spatiotemporal regulation of insulin signaling by liquid–liquid phase separation

Insulin signals through its receptor to recruit insulin receptor substrates (IRS) and phosphatidylinositol 3-kinase (PI3K) to the plasma membrane for production of phosphatidylinositol-3,4,5-trisphosphate (PIP3) from phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], which consequently activates pro...

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Detalles Bibliográficos
Autores principales: Zhou, Kun, Chen, Qiaoli, Chen, Jiamou, Liang, Derong, Feng, Weikuan, Liu, Minjun, Wang, Qi, Wang, Ruizhen, Ouyang, Qian, Quan, Chao, Chen, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256590/
https://www.ncbi.nlm.nih.gov/pubmed/35790738
http://dx.doi.org/10.1038/s41421-022-00430-1

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