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Virtual reality for the observation of oncology models (VROOM): immersive analytics for oncology patient cohorts

The significant advancement of inexpensive and portable virtual reality (VR) and augmented reality devices has re-energised the research in the immersive analytics field. The immersive environment is different from a traditional 2D display used to analyse 3D data as it provides a unified environment...

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Autores principales: Lau, Chng Wei, Qu, Zhonglin, Draper, Daniel, Quan, Rosa, Braytee, Ali, Bluff, Andrew, Zhang, Dongmo, Johnston, Andrew, Kennedy, Paul J., Simoff, Simeon, Nguyen, Quang Vinh, Catchpoole, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256599/
https://www.ncbi.nlm.nih.gov/pubmed/35790803
http://dx.doi.org/10.1038/s41598-022-15548-1
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author Lau, Chng Wei
Qu, Zhonglin
Draper, Daniel
Quan, Rosa
Braytee, Ali
Bluff, Andrew
Zhang, Dongmo
Johnston, Andrew
Kennedy, Paul J.
Simoff, Simeon
Nguyen, Quang Vinh
Catchpoole, Daniel
author_facet Lau, Chng Wei
Qu, Zhonglin
Draper, Daniel
Quan, Rosa
Braytee, Ali
Bluff, Andrew
Zhang, Dongmo
Johnston, Andrew
Kennedy, Paul J.
Simoff, Simeon
Nguyen, Quang Vinh
Catchpoole, Daniel
author_sort Lau, Chng Wei
collection PubMed
description The significant advancement of inexpensive and portable virtual reality (VR) and augmented reality devices has re-energised the research in the immersive analytics field. The immersive environment is different from a traditional 2D display used to analyse 3D data as it provides a unified environment that supports immersion in a 3D scene, gestural interaction, haptic feedback and spatial audio. Genomic data analysis has been used in oncology to understand better the relationship between genetic profile, cancer type, and treatment option. This paper proposes a novel immersive analytics tool for cancer patient cohorts in a virtual reality environment, virtual reality to observe oncology data models. We utilise immersive technologies to analyse the gene expression and clinical data of a cohort of cancer patients. Various machine learning algorithms and visualisation methods have also been deployed in VR to enhance the data interrogation process. This is supported with established 2D visual analytics and graphical methods in bioinformatics, such as scatter plots, descriptive statistical information, linear regression, box plot and heatmap into our visualisation. Our approach allows the clinician to interrogate the information that is familiar and meaningful to them while providing them immersive analytics capabilities to make new discoveries toward personalised medicine.
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spelling pubmed-92565992022-07-07 Virtual reality for the observation of oncology models (VROOM): immersive analytics for oncology patient cohorts Lau, Chng Wei Qu, Zhonglin Draper, Daniel Quan, Rosa Braytee, Ali Bluff, Andrew Zhang, Dongmo Johnston, Andrew Kennedy, Paul J. Simoff, Simeon Nguyen, Quang Vinh Catchpoole, Daniel Sci Rep Article The significant advancement of inexpensive and portable virtual reality (VR) and augmented reality devices has re-energised the research in the immersive analytics field. The immersive environment is different from a traditional 2D display used to analyse 3D data as it provides a unified environment that supports immersion in a 3D scene, gestural interaction, haptic feedback and spatial audio. Genomic data analysis has been used in oncology to understand better the relationship between genetic profile, cancer type, and treatment option. This paper proposes a novel immersive analytics tool for cancer patient cohorts in a virtual reality environment, virtual reality to observe oncology data models. We utilise immersive technologies to analyse the gene expression and clinical data of a cohort of cancer patients. Various machine learning algorithms and visualisation methods have also been deployed in VR to enhance the data interrogation process. This is supported with established 2D visual analytics and graphical methods in bioinformatics, such as scatter plots, descriptive statistical information, linear regression, box plot and heatmap into our visualisation. Our approach allows the clinician to interrogate the information that is familiar and meaningful to them while providing them immersive analytics capabilities to make new discoveries toward personalised medicine. Nature Publishing Group UK 2022-07-05 /pmc/articles/PMC9256599/ /pubmed/35790803 http://dx.doi.org/10.1038/s41598-022-15548-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Lau, Chng Wei
Qu, Zhonglin
Draper, Daniel
Quan, Rosa
Braytee, Ali
Bluff, Andrew
Zhang, Dongmo
Johnston, Andrew
Kennedy, Paul J.
Simoff, Simeon
Nguyen, Quang Vinh
Catchpoole, Daniel
Virtual reality for the observation of oncology models (VROOM): immersive analytics for oncology patient cohorts
title Virtual reality for the observation of oncology models (VROOM): immersive analytics for oncology patient cohorts
title_full Virtual reality for the observation of oncology models (VROOM): immersive analytics for oncology patient cohorts
title_fullStr Virtual reality for the observation of oncology models (VROOM): immersive analytics for oncology patient cohorts
title_full_unstemmed Virtual reality for the observation of oncology models (VROOM): immersive analytics for oncology patient cohorts
title_short Virtual reality for the observation of oncology models (VROOM): immersive analytics for oncology patient cohorts
title_sort virtual reality for the observation of oncology models (vroom): immersive analytics for oncology patient cohorts
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256599/
https://www.ncbi.nlm.nih.gov/pubmed/35790803
http://dx.doi.org/10.1038/s41598-022-15548-1
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