Hyaluronan synthase 2, a target of miR-200c, promotes carbon tetrachloride-induced acute and chronic liver inflammation via regulation of CCL3 and CCL4

Liver fibrosis occurs during wound healing after repeated liver injury and is characterized by extensive extracellular matrix deposition. We previously identified hyaluronan synthase 2 (HAS2) as a driver of liver fibrosis and hepatic stellate cell (HSC) activation. Developing strategies to suppress...

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Detalles Bibliográficos
Autores principales: Kim, Sun Myoung, Song, Ga Yeon, Shim, Aeri, Lee, Jee Hyung, Eom, Cheol Bin, Liu, Cheng, Yang, Yoon Mee, Seki, Ekihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256637/
https://www.ncbi.nlm.nih.gov/pubmed/35662287
http://dx.doi.org/10.1038/s12276-022-00781-5

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