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Gastric hydrodistension CT versus CT without gastric distension in preoperative TN staging of gastric carcinoma: analysis of single-center cancer registry

Accurate staging of gastric cancer is essential for the selection and optimization of therapy. Hydrodistension of the stomach is recommended to improve the accuracy of preoperative staging with contrast-enhanced multidetector computed tomography (MDCT). This study compares the performance of contras...

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Autores principales: Lee, Yu-Hsien, Chan, Wen-Hui, Lai, Ying-Chieh, Chen, An-Hsin, Chen, Chien-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256680/
https://www.ncbi.nlm.nih.gov/pubmed/35790760
http://dx.doi.org/10.1038/s41598-022-15619-3
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author Lee, Yu-Hsien
Chan, Wen-Hui
Lai, Ying-Chieh
Chen, An-Hsin
Chen, Chien-Ming
author_facet Lee, Yu-Hsien
Chan, Wen-Hui
Lai, Ying-Chieh
Chen, An-Hsin
Chen, Chien-Ming
author_sort Lee, Yu-Hsien
collection PubMed
description Accurate staging of gastric cancer is essential for the selection and optimization of therapy. Hydrodistension of the stomach is recommended to improve the accuracy of preoperative staging with contrast-enhanced multidetector computed tomography (MDCT). This study compares the performance of contrast-enhanced gastric water distension versus a nondistension MDCT protocol for T and N staging and serosal invasion in comparison to surgical histopathology. After propensity score matching, 86 patients in each group were included for analysis. The overall accuracy of distension versus nondistension group in T staging was 45% (95% CI 35–56) and 55% (95% CI 44–65), respectively (p = 0.29). There was no difference in the sensitivity and specificity in individual T staging and assessment of serosal invasion (all p > 0.41). Individual stage concordance with pathology was not significantly different (all p > 0.41). The overall accuracy of N staging was the same for distension and nondistension groups (51% [95% CI 40–62]). The majority of N0 staging (78–81%) were correctly staged, whereas N3 staging cases (63–68%) were predominantly understaged. In summary, there was no significant difference in the diagnostic performance of individual TN staging and assessment of serosal invasion using MDCT with or without gastric water distension.
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spelling pubmed-92566802022-07-07 Gastric hydrodistension CT versus CT without gastric distension in preoperative TN staging of gastric carcinoma: analysis of single-center cancer registry Lee, Yu-Hsien Chan, Wen-Hui Lai, Ying-Chieh Chen, An-Hsin Chen, Chien-Ming Sci Rep Article Accurate staging of gastric cancer is essential for the selection and optimization of therapy. Hydrodistension of the stomach is recommended to improve the accuracy of preoperative staging with contrast-enhanced multidetector computed tomography (MDCT). This study compares the performance of contrast-enhanced gastric water distension versus a nondistension MDCT protocol for T and N staging and serosal invasion in comparison to surgical histopathology. After propensity score matching, 86 patients in each group were included for analysis. The overall accuracy of distension versus nondistension group in T staging was 45% (95% CI 35–56) and 55% (95% CI 44–65), respectively (p = 0.29). There was no difference in the sensitivity and specificity in individual T staging and assessment of serosal invasion (all p > 0.41). Individual stage concordance with pathology was not significantly different (all p > 0.41). The overall accuracy of N staging was the same for distension and nondistension groups (51% [95% CI 40–62]). The majority of N0 staging (78–81%) were correctly staged, whereas N3 staging cases (63–68%) were predominantly understaged. In summary, there was no significant difference in the diagnostic performance of individual TN staging and assessment of serosal invasion using MDCT with or without gastric water distension. Nature Publishing Group UK 2022-07-05 /pmc/articles/PMC9256680/ /pubmed/35790760 http://dx.doi.org/10.1038/s41598-022-15619-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Lee, Yu-Hsien
Chan, Wen-Hui
Lai, Ying-Chieh
Chen, An-Hsin
Chen, Chien-Ming
Gastric hydrodistension CT versus CT without gastric distension in preoperative TN staging of gastric carcinoma: analysis of single-center cancer registry
title Gastric hydrodistension CT versus CT without gastric distension in preoperative TN staging of gastric carcinoma: analysis of single-center cancer registry
title_full Gastric hydrodistension CT versus CT without gastric distension in preoperative TN staging of gastric carcinoma: analysis of single-center cancer registry
title_fullStr Gastric hydrodistension CT versus CT without gastric distension in preoperative TN staging of gastric carcinoma: analysis of single-center cancer registry
title_full_unstemmed Gastric hydrodistension CT versus CT without gastric distension in preoperative TN staging of gastric carcinoma: analysis of single-center cancer registry
title_short Gastric hydrodistension CT versus CT without gastric distension in preoperative TN staging of gastric carcinoma: analysis of single-center cancer registry
title_sort gastric hydrodistension ct versus ct without gastric distension in preoperative tn staging of gastric carcinoma: analysis of single-center cancer registry
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256680/
https://www.ncbi.nlm.nih.gov/pubmed/35790760
http://dx.doi.org/10.1038/s41598-022-15619-3
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