Spatial regulation of AMPK signaling revealed by a sensitive kinase activity reporter

AMP-activated protein kinase (AMPK) is a master regulator of cellular energetics which coordinates metabolism by phosphorylating a plethora of substrates throughout the cell. But how AMPK activity is regulated at different subcellular locations for precise spatiotemporal control over metabolism is u...

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Detalles Bibliográficos
Autores principales: Schmitt, Danielle L., Curtis, Stephanie D., Lyons, Anne C., Zhang, Jin-fan, Chen, Mingyuan, He, Catherine Y., Mehta, Sohum, Shaw, Reuben J., Zhang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256702/
https://www.ncbi.nlm.nih.gov/pubmed/35790710
http://dx.doi.org/10.1038/s41467-022-31190-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256702/
https://www.ncbi.nlm.nih.gov/pubmed/35790710
http://dx.doi.org/10.1038/s41467-022-31190-x

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