Oncogenic TRIB2 interacts with and regulates PKM2 to promote aerobic glycolysis and lung cancer cell procession

PKM2 is an important regulator of the aerobic glycolysis that plays a vital role in cancer cell metabolic reprogramming. In general, Trib2 is considered as a “pseudokinase”, contributing to different kinds of cancer. However, the detailed roles of TRIB2 in regulating cancer metabolism by PKM2 remain...

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Detalles Bibliográficos
Autores principales: Liu, Yuan-Rong, Song, Dan-Dan, Liang, Dong-Min, Li, You-Jie, Yan, Yun-Fei, Sun, Hong-Fang, Zhang, Mei-Ling, Hu, Jin-Xia, Zhao, Yu-Long, Liang, Yan, Li, Yan-Mei, Yang, Zhen, Wang, Ran-Ran, Zheng, Hou-Feng, Wang, Pingyu, Xie, Shu-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256704/
https://www.ncbi.nlm.nih.gov/pubmed/35790734
http://dx.doi.org/10.1038/s41420-022-01095-1

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