Cargando…

High Levels of DEAH-Box Helicases Relate to Poor Prognosis and Reduction of DHX9 Improves Radiosensitivity of Hepatocellular Carcinoma

BACKGROUND: Liver hepatocellular carcinoma (LIHC), one of the most common primary malignancies, exhibits high levels of molecular and clinical heterogeneity. Increasing evidence has confirmed the important roles of some RNA helicase families in tumor development, but the function of the DEAH-box RNA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Xi, Lin, Letao, Chen, Guanyu, Yan, Huzheng, Li, Zhenyu, Xiao, Meigui, He, Xu, Zhang, Fujun, Zhang, Yanling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256992/ https://www.ncbi.nlm.nih.gov/pubmed/35814441 http://dx.doi.org/10.3389/fonc.2022.900671

Ejemplares similares

Bidirectional regulation of adenosine-to-inosine (A-to-I) RNA editing by DEAH box helicase 9 (DHX9) in cancer
por: Hong, HuiQi, et al.
Publicado: (2018)

Structure and function of DEAH-box helicase 32 and its role in cancer
por: Wei, Qingchun, et al.
Publicado: (2021)

Insights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase
por: Chen, Michael C., et al.
Publicado: (2015)

Mechanism of recognition of parallel G-quadruplexes by DEAH/RHAU helicase DHX36 explored by molecular dynamics simulations
por: Hossain, Kazi Amirul, et al.
Publicado: (2021)

Structural insights into the mechanism of the DEAH-box RNA helicase Prp43
por: Tauchert, Marcel J, et al.
Publicado: (2017)

Diverse Roles of DEAD/DEAH-Box Helicases in Innate Immunity and Diseases
por: Perčulija, Vanja, et al.
Publicado: (2019)

Pathogenic variants in the DEAH-box RNA helicase DHX37 are a frequent cause of 46,XY gonadal dysgenesis and 46,XY testicular regression syndrome
por: McElreavey, Ken, et al.
Publicado: (2019)

The DEAD/DEAH box helicase, DDX11, is essential for the survival of advanced melanomas
por: Bhattacharya, Chitralekha, et al.
Publicado: (2012)

A novel DEAH-box helicase 37 mutation associated with differences of sex development
por: Wan, Yun, et al.
Publicado: (2023)

MoDHX35, a DEAH-Box Protein, Is Required for Appressoria Formation and Full Virulence of the Rice Blast Fungus, Magnaporthe oryzae
por: Ying, Shumin, et al.
Publicado: (2022)

Crystal structures of the DExH-box RNA helicase DHX9
por: Lee, Young-Tae, et al.
Publicado: (2023)

Regulation of DEAH/RHA Helicases by G-Patch Proteins
por: Robert-Paganin, Julien, et al.
Publicado: (2015)

psiCLIP reveals dynamic RNA binding by DEAH-box helicases before and after exon ligation
por: Strittmatter, Lisa M., et al.
Publicado: (2021)

Conformational dynamics of the RNA binding channel regulates loading and translocation of the DEAH-box helicase Prp43
por: Enders, Marieke, et al.
Publicado: (2023)

Circular RNA circEYA3 promotes the radiation resistance of hepatocellular carcinoma via the IGF2BP2/DTX3L axis
por: Hu, Pan, et al.
Publicado: (2023)

Tumor Cell Survival Dependence on the DHX9 DExH-Box Helicase
por: Lee, Teresa, et al.
Publicado: (2016)

HrpA, a DEAH-Box RNA Helicase, Is Involved in Global Gene Regulation in the Lyme Disease Spirochete
por: Salman-Dilgimen, Aydan, et al.
Publicado: (2011)

The DEAH-box RNA helicase RHAU binds an intramolecular RNA G-quadruplex in TERC and associates with telomerase holoenzyme
por: Lattmann, Simon, et al.
Publicado: (2011)

Structural basis for DEAH-helicase activation by G-patch proteins
por: Studer, Michael K., et al.
Publicado: (2020)

Dependence of p53-deficient cells on the DHX9 DExH-box helicase
por: Lee, Teresa, et al.
Publicado: (2017)

Continuous millisecond conformational cycle of a DEAH box helicase reveals control of domain motions by atomic-scale transitions
por: Becker, Robert A., et al.
Publicado: (2023)

Structural basis for RNA translocation by DEAH-box ATPases
por: Hamann, Florian, et al.
Publicado: (2019)

Role of the amino terminal RHAU-specific motif in the recognition and resolution of guanine quadruplex-RNA by the DEAH-box RNA helicase RHAU
por: Lattmann, Simon, et al.
Publicado: (2010)

The DEAH-box Helicase Dhr1 Dissociates U3 from the Pre-rRNA to Promote Formation of the Central Pseudoknot
por: Sardana, Richa, et al.
Publicado: (2015)

DEAH-box polypeptide 32 promotes hepatocellular carcinoma progression via activating the β-catenin pathway
por: Hu, Xiaoyun, et al.
Publicado: (2021)

Crystal structure of the spliceosomal DEAH-box ATPase Prp2
por: Schmitt, Andreas, et al.
Publicado: (2018)

Human Nup98 regulates the localization and activity of DExH/D-box helicase DHX9
por: Capitanio, Juliana S, et al.
Publicado: (2017)

The DEAH-box RNA helicase Dhr1 contains a remarkable carboxyl terminal domain essential for small ribosomal subunit biogenesis
por: Roychowdhury, Amlan, et al.
Publicado: (2019)

The DEAD-box RNA helicase Dhx15 controls glycolysis and arbovirus replication in Aedes aegypti mosquito cells
por: Rosendo Machado, Samara, et al.
Publicado: (2022)

TFIP11 Interacts with mDEAH9, an RNA Helicase Involved in Spliceosome Disassembly
por: Wen, Xin, et al.
Publicado: (2008)

Regulation of the DEAH/RHA helicase Prp43 by the G-patch factor Pfa1
por: Enders, Marieke, et al.
Publicado: (2022)

DNA/RNA helicase DHX36 is required for late stages of spermatogenesis
por: Zhang, Kejia, et al.
Publicado: (2022)

The DEAD/DEAH Box Helicase, DDX11, Is Essential for the Survival of Advanced Clear Cell Renal Cell Carcinoma and Is a Determinant of PARP Inhibitor Sensitivity
por: Park, Jee Soo, et al.
Publicado: (2021)

The enigmatic helicase DHX9 and its association with the hallmarks of cancer
por: Gulliver, Chloe, et al.
Publicado: (2020)

Functional link between DEAH/RHA helicase Prp43 activation and ATP base binding
por: Robert-Paganin, Julien, et al.
Publicado: (2017)

Clinical efficacy of CT-guided (125)I brachytherapy in patients with local residual or recurrent hepatocellular carcinoma after thermal ablation
por: Zhu, Wenliang, et al.
Publicado: (2022)

Learning and Investigation of the Role of Angiotensin-Converting Enzyme in Radiotherapy for Nasopharyngeal Carcinoma
por: Ding, Yanan, et al.
Publicado: (2023)

Targeting RNA helicase DHX33 blocks Ras‐driven lung tumorigenesis in vivo
por: Wang, Xingshun, et al.
Publicado: (2020)

DEAH-RHA helicase•Znf cofactor systems in kinetoplastid RNA editing and evolutionarily distant RNA processes
por: Cruz-Reyes, Jorge, et al.
Publicado: (2016)

Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility
por: Grass, Lena M., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_t4bvho99a860fomgb52tb2sk3r