Cargando…

GW4064 Alters Gut Microbiota Composition and Counteracts Autism-Associated Behaviors in BTBR T+tf/J Mice

Autism spectrum disorder (ASD) is considered a heterogeneous neurodevelopmental disorder characterized by significant social, communication, and behavioral impairments. The gut microbiota is increasingly considered a promising therapeutic target in ASD. Farnesoid X receptor (FXR) has recently been s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Jiayin, Liu, Chuanqi, Gao, Zhanyuan, Zhou, Lianyu, Gao, Junwei, Luo, Yi, Liu, Tianyao, Fan, Xiaotang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257030/ https://www.ncbi.nlm.nih.gov/pubmed/35811667 http://dx.doi.org/10.3389/fcimb.2022.911259

Ejemplares similares

Alteration of Gut Microbiota: New Strategy for Treating Autism Spectrum Disorder
por: Liu, Jiayin, et al.
Publicado: (2022)

Unusual Repertoire of Vocalizations in the BTBR T+tf/J Mouse Model of Autism
por: Scattoni, Maria Luisa, et al.
Publicado: (2008)

Inflammatory macrophage phenotype in BTBR T+tf/J mice
por: Onore, Charity E., et al.
Publicado: (2013)

Metformin Administration During Early Postnatal Life Rescues Autistic-Like Behaviors in the BTBR T+ Itpr3tf/J Mouse Model of Autism
por: Wang, Lian, et al.
Publicado: (2018)

Effect of FXR agonist GW4064 in the treatment of hilar cholangiocarcinoma in rats
por: Wang, Jie-ping, et al.
Publicado: (2022)

Neuroimaging Evidence of Major Morpho-Anatomical and Functional Abnormalities in the BTBR T+TF/J Mouse Model of Autism
por: Dodero, Luca, et al.
Publicado: (2013)

Neuronal correlates of asocial behavior in a BTBR T(+)Itpr3(tf)/J mouse model of autism
por: Meyza, Ksenia, et al.
Publicado: (2015)

Altered meningeal immunity contributing to the autism-like behavior of BTBR T(+)Itpr3(tf)/J mice
por: Uddin, Mohammad Nizam, et al.
Publicado: (2022)

Oxotremorine treatment reduces repetitive behaviors in BTBR T+ tf/J mice
por: Amodeo, Dionisio A., et al.
Publicado: (2014)

FXR agonist GW4064 enhances anti-PD-L1 immunotherapy in colorectal cancer
por: Lu, Lu, et al.
Publicado: (2023)

Quantitative Trait Loci for Interhemispheric Commissure Development and Social Behaviors in the BTBR T(+) tf/J Mouse Model of Autism
por: Jones-Davis, Dorothy M., et al.
Publicado: (2013)

Humulus japonicus rescues autistic-like behaviours in the BTBR T(+) Itpr3(tf)/J mouse model of autism
por: Park, Hye-Yeon, et al.
Publicado: (2021)

Effect of social odor context on the emission of isolation-induced ultrasonic vocalizations in the BTBR T+tf/J mouse model for autism
por: Wöhr, Markus
Publicado: (2015)

Enhancement of Short-Term Memory by Methyl-6-(Phenylethynyl)-Pyridine in the BTBR T+tf/J Mouse Model of Autism Spectrum Disorder
por: Yang, Haijie, et al.
Publicado: (2015)

Tissue Specific Impacts of a Ketogenic Diet on Mitochondrial Dynamics in the BTBR(T+tf/j) Mouse
por: Newell, Christopher, et al.
Publicado: (2016)

Social deficits in BTBR T+ Itpr3tf/J mice vary with ecological validity of the test
por: Winiarski, Maciej, et al.
Publicado: (2022)

Cadmium Exposure Is Associated with Behavioral Deficits and Neuroimmune Dysfunction in BTBR T(+) Itpr3tf/J Mice
por: Alanazi, Mohammed M., et al.
Publicado: (2023)

Cerebellar Oxidative DNA Damage and Altered DNA Methylation in the BTBR T+tf/J Mouse Model of Autism and Similarities with Human Post Mortem Cerebellum
por: Shpyleva, Svitlana, et al.
Publicado: (2014)

Simultaneous Blockade of Histamine H(3) Receptors and Inhibition of Acetylcholine Esterase Alleviate Autistic-Like Behaviors in BTBR T+ tf/J Mouse Model of Autism
por: Eissa, Nermin, et al.
Publicado: (2020)

Validation of operant social motivation paradigms using BTBR T+tf/J and C57BL/6J inbred mouse strains
por: Martin, Loren, et al.
Publicado: (2014)

General Anesthesia During Neurodevelopment Reduces Autistic Behavior in Adult BTBR Mice, a Murine Model of Autism
por: Cui, Jianchen, et al.
Publicado: (2021)

Premature changes in neuronal excitability account for hippocampal network impairment and autistic-like behavior in neonatal BTBR T+tf/J mice
por: Cellot, Giada, et al.
Publicado: (2016)

Characterization of behavioral phenotypes in the BTBR T(+) Itpr3(tf)/J mouse model of autism spectrum disorder under social housing conditions using the multiple animal positioning system
por: Endo, Nozomi, et al.
Publicado: (2019)

Corrigendum: Premature changes in neuronal excitability account for hippocampal network impairment and autistic-like behavior in neonatal BTBR T+tf/J mice
por: Cellot, Giada, et al.
Publicado: (2017)

Alteration of peripheral cortisol and autism spectrum disorder: A meta-analysis
por: Gao, Junwei, et al.
Publicado: (2022)

Effects of the Female Estrous Cycle on the Sexual Behaviors and Ultrasonic Vocalizations of Male C57BL/6 and Autistic BTBR T+ tf/J Mice
por: Kim, Hyopil, et al.
Publicado: (2016)

Changes in the Fluorescence Tracking of NaV1.6 Protein Expression in a BTBR T+Itpr3tf/J Autistic Mouse Model
por: Alshammari, Musaad A., et al.
Publicado: (2019)

Effects of environmental enrichment and sexual dimorphism on the expression of cerebellar receptors in C57BL/6 and BTBR + Itpr3tf/J mice
por: Monje-Reyna, Daniela, et al.
Publicado: (2022)

The Exposure to Lead (Pb) Exacerbates Immunological Abnormalities in BTBR T(+) Itpr(3tf)/J Mice through the Regulation of Signaling Pathways Relevant to T Cells
por: Assiri, Mohammed A., et al.
Publicado: (2023)

GW4064 attenuates lipopolysaccharide-induced hepatic inflammation and apoptosis through inhibition of the Toll-like receptor 4-mediated p38 mitogen-activated protein kinase signaling pathway in mice
por: Liu, Hsuan-Miao, et al.
Publicado: (2018)

Involvement of Intestinal Goblet Cells and Changes in Sodium Glucose Transporters Expression: Possible Therapeutic Targets in Autistic BTBR T(+)Itpr3(tf)/J Mice
por: Franco, Caterina, et al.
Publicado: (2021)

Exposure to Methylmercury at Juvenile Stage Worsens Autism-Like Symptoms in Adult BTBR T+tf/J Mice Due to Lack of Nuclear Factor Erythroid 2-Related Factor 2 Signaling Upregulation in Periphery and Brain
por: Algahtani, Mohammad M., et al.
Publicado: (2023)

Dengue activates mTORC2 signaling to counteract apoptosis and maximize viral replication
por: Carter, Christoph C., et al.
Publicado: (2022)

Herpes Simplex Virus 1 Counteracts Tetherin Restriction via Its Virion Host Shutoff Activity
por: Zenner, Helen L., et al.
Publicado: (2013)

Imbalance in the Gut Microbiota of Children With Autism Spectrum Disorders
por: Ding, Hongfang, et al.
Publicado: (2021)

The effects of aging on the BTBR mouse model of autism spectrum disorder
por: Jasien, Joan M., et al.
Publicado: (2014)

Ketogenic Diet Improves Core Symptoms of Autism in BTBR Mice
por: Ruskin, David N., et al.
Publicado: (2013)

Zinc Water Prevents Autism-Like Behaviors in the BTBR Mice
por: Zhang, Li, et al.
Publicado: (2023)

Social Approach Behaviors are Similar on Conventional Versus Reverse Lighting Cycles, and in Replications Across Cohorts, in BTBR T+ tf/J, C57BL/6J, and Vasopressin Receptor 1B Mutant Mice
por: Yang, Mu, et al.
Publicado: (2007)

Nanoformulated Bumetanide Ameliorates Social Deficiency in BTBR Mice Model of Autism Spectrum Disorder
por: Lv, Hui, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_i35nq6ce1i10m3v164ujggjh22