Cargando…

DNA Damage Response Gene-Based Subtypes Associated With Clinical Outcomes in Early-Stage Lung Adenocarcinoma

DNA damage response (DDR) pathways play a crucial role in lung cancer. In this retrospective analysis, we aimed to develop a prognostic model and molecular subtype based on the expression profiles of DDR-related genes in early-stage lung adenocarcinoma (LUAD). A total of 1,785 lung adenocarcinoma sa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Yang, Qing, Bei, Xu, Chunwei, Zhao, Jing, Liao, Yuchen, Cui, Peng, Wang, Guoqiang, Cai, Shangli, Song, Yong, Cao, Liming, Duan, Jianchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257065/ https://www.ncbi.nlm.nih.gov/pubmed/35813819 http://dx.doi.org/10.3389/fmolb.2022.901829

Ejemplares similares

An integrated analysis of prognostic mRNA signature in early- and progressive-stage gastric adenocarcinoma
por: Hong, Xiaoling, et al.
Publicado: (2023)

Identification of TRP-Related Subtypes, Development of a Prognostic Model, and Characterization of Tumor Microenvironment Infiltration in Lung Adenocarcinoma
por: Sun, Sibo, et al.
Publicado: (2022)

Characterization of an Aging-Based Diagnostic Gene Signature and Molecular Subtypes With Diverse Immune Infiltrations in Atherosclerosis
por: Zhao, Lei, et al.
Publicado: (2022)

Quantitative Analysis of the Protein Methylome Reveals PARP1 Methylation is involved in DNA Damage Response
por: Wang, Xinzhu, et al.
Publicado: (2022)

Identification of Molecular Subtypes and Key Genes of Atherosclerosis Through Gene Expression Profiles
por: Yang, Yujia, et al.
Publicado: (2021)

Identifying Robust Microbiota Signatures and Interpretable Rules to Distinguish Cancer Subtypes
por: Chen, Lei, et al.
Publicado: (2020)

Prognostic value, immune signature and molecular mechanisms of the SUMO family in pancreatic adenocarcinoma
por: Duan, Yunjie, et al.
Publicado: (2022)

Novel Molecular Subtypes Associated With 5mC Methylation and Their Role in Hepatocellular Carcinoma Immunotherapy
por: Mo, Zhuomao, et al.
Publicado: (2020)

Prognostic Implications and Immune Infiltration Characteristics of Chromosomal Instability-Related Dysregulated CeRNA in Lung Adenocarcinoma
por: Guo, Shengnan, et al.
Publicado: (2022)

Mechanisms for Maintaining Eukaryotic Replisome Progression in the Presence of DNA Damage
por: Guilliam, Thomas A.
Publicado: (2021)

Searching for DNA Damage: Insights From Single Molecule Analysis
por: Schaich, Matthew A., et al.
Publicado: (2021)

Extracellular Matrix-Based Gene Expression Signature Defines Two Prognostic Subtypes of Hepatocellular Carcinoma With Different Immune Microenvironment Characteristics
por: Tang, Hui, et al.
Publicado: (2022)

Gene Expression Subtyping Reveals Immune alterations:TCGA Database for Prognosis in Ovarian Serous Cystadenocarcinoma
por: Feng, Chunxia, et al.
Publicado: (2021)

Upregulation of GNPNAT1 Predicts Poor Prognosis and Correlates With Immune Infiltration in Lung Adenocarcinoma
por: Liu, Wenting, et al.
Publicado: (2021)

Identification of an Immunologic Signature of Lung Adenocarcinomas Based on Genome-Wide Immune Expression Profiles
por: Ling, Bo, et al.
Publicado: (2021)

N6-Methyladenosine Methylation Regulator RBM15 is a Potential Prognostic Biomarker and Promotes Cell Proliferation in Pancreatic Adenocarcinoma
por: Zhao, Zhiying, et al.
Publicado: (2022)

Fumarase: From the TCA Cycle to DNA Damage Response and Tumor Suppression
por: Leshets, Michael, et al.
Publicado: (2018)

Nucleosome Remodeling by Fun30(SMARCAD1) in the DNA Damage Response
por: Bantele, Susanne C. S., et al.
Publicado: (2019)

MicroRNA-125b-5p Correlates With Prognosis and Lung Adenocarcinoma Progression
por: Tang, Lin, et al.
Publicado: (2022)

Establishment and validation of a prognostic signature for pancreatic ductal adenocarcinoma based on lactate metabolism-related genes
por: Huang, Xin, et al.
Publicado: (2023)

Identifying a novel cuproptosis-related necroptosis gene subtype-related signature for predicting the prognosis, tumor microenvironment, and immunotherapy of hepatocellular carcinoma
por: Shi, Yuanxin, et al.
Publicado: (2023)

The Prognostic Model and Drug Sensitivity of LKB1-Mutant Lung Adenocarcinoma Based on Immune Landscape
por: Wang, Guanghui, et al.
Publicado: (2022)

Serum Extracellular Vesicle–Derived miR-124-3p as a Diagnostic and Predictive Marker for Early-Stage Acute Ischemic Stroke
por: Qi, Zheng, et al.
Publicado: (2021)

Independent Evolution of Strychnine Recognition by Bitter Taste Receptor Subtypes
por: Xue, Ava Yuan, et al.
Publicado: (2018)

Identification of microRNA editing sites in three subtypes of leukemia
por: Xie, Wenping, et al.
Publicado: (2022)

Construction of a ceRNA Network and Analysis of Tumor Immune Infiltration in Pancreatic Adenocarcinoma
por: Xiao, Jingjing, et al.
Publicado: (2021)

Molecular characterization of colorectal mucinous adenocarcinoma and adenocarcinoma, not otherwise specified, identified by multiomic data analysis
por: Xu, Kailun, et al.
Publicado: (2023)

Requirements for MRN endonuclease processing of topoisomerase II-mediated DNA damage in mammalian cells
por: Sun, Yilun, et al.
Publicado: (2022)

Corrigendum: Independent Evolution of Strychnine Recognition by Bitter Taste Receptor Subtypes
por: Xue, Ava Yuan, et al.
Publicado: (2018)

Beyond the Trinity of ATM, ATR, and DNA-PK: Multiple Kinases Shape the DNA Damage Response in Concert With RNA Metabolism
por: Burger, Kaspar, et al.
Publicado: (2019)

Diaphanous-related formin subfamily: Novel prognostic biomarkers and tumor microenvironment regulators for pancreatic adenocarcinoma
por: Zhang, Bixi, et al.
Publicado: (2022)

ZEB1: A Critical Regulator of Cell Plasticity, DNA Damage Response, and Therapy Resistance
por: Drápela, Stanislav, et al.
Publicado: (2020)

MiR-4521 perturbs FOXM1-mediated DNA damage response in breast cancer
por: Kuthethur, Raviprasad, et al.
Publicado: (2023)

The Integrative Analysis Identifies Three Cancer Subtypes and Stemness Features in Cutaneous Melanoma
por: Wang, Xiaoran, et al.
Publicado: (2021)

Identification of a Novel Tumor Microenvironment–Associated Eight-Gene Signature for Prognosis Prediction in Lung Adenocarcinoma
por: Ma, Chao, et al.
Publicado: (2020)

SNX20AR/MiRNA-301a-3p/SNX20 Axis Associated With Cell Proliferation and Immune Infiltration in Lung Adenocarcinoma
por: Yuan, Yixiao, et al.
Publicado: (2021)

Comprehensive Analysis of Aquaporin Superfamily in Lung Adenocarcinoma
por: Lin, Guofu, et al.
Publicado: (2021)

USF1 Transcriptionally Regulates UGT1A3 and Promotes Lung Adenocarcinoma Progression by Regulating Neurotrophin Signaling Pathway
por: Wang, Yu, et al.
Publicado: (2022)

Prognostic value, immune signature and molecular mechanisms of the APOBEC family members APOBEC1, APOBEC3A, APOBEC3G and APOBEC3H in pancreatic adenocarcinoma
por: Duan, Yunjie, et al.
Publicado: (2022)

Establishment of Novel Prostate Cancer Risk Subtypes and A Twelve-Gene Prognostic Model
por: Zhang, Enchong, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_krl2iaanpc3nsjtj2n9m27236i