Gut Microbiota-Derived Diaminopimelic Acid Promotes the NOD1/RIP2 Signaling Pathway and Plays a Key Role in the Progression of Severe Acute Pancreatitis

Impaired intestinal barrier function and gut microbiota dysbiosis are believed to be related to exacerbation of acute pancreatitis (AP). As a bacterial cell wall peptidoglycan component, diaminopimelic acid (DAP) is a specific ligand of NOD1 that regulates the NOD1/RIP2/NF-kB signaling pathway. Here...

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Detalles Bibliográficos
Autores principales: Jiao, Juying, Liu, Jianjun, Li, Qi, Zhang, Guixin, Pan, Chen, Luo, Fei, Zhang, Qingkai, Qi, Bing, Zhao, Liang, Yin, Peiyuan, Shang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257083/
https://www.ncbi.nlm.nih.gov/pubmed/35811665
http://dx.doi.org/10.3389/fcimb.2022.838340

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