Spike-heparan sulfate interactions in SARS-CoV-2 infection

Recent biochemical, biophysical, and genetic studies have shown that heparan sulfate, a major component of the cellular glycocalyx, participates in infection of SARS-CoV-2 by facilitating the so-called open conformation of the spike protein, which is required for binding to ACE2. This review highlig...

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Detalles Bibliográficos
Autores principales: Kearns, Fiona L., Sandoval, Daniel R., Casalino, Lorenzo, Clausen, Thomas M., Rosenfeld, Mia A., Spliid, Charlotte B., Amaro, Rommie E., Esko, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257145/
https://www.ncbi.nlm.nih.gov/pubmed/35926454
http://dx.doi.org/10.1016/j.sbi.2022.102439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257145/
https://www.ncbi.nlm.nih.gov/pubmed/35926454
http://dx.doi.org/10.1016/j.sbi.2022.102439

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