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Intranasal administration of a live-attenuated recombinant newcastle disease virus expressing the SARS-CoV-2 Spike protein induces high neutralizing antibody levels and protects from experimental challenge infection in hamsters

The emergence of SARS-CoV-2 in December 2019 resulted in the COVID-19 pandemic. Recurring disease outbreaks repeatedly overloaded the public health sector and severely affected the global economy. We developed a candidate COVID-19 vaccine based on a recombinant Newcastle disease virus (NDV) vaccine...

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Detalles Bibliográficos
Autores principales:	de Swart, Rik L., de Leeuw, Olav S., Oreshkova, Nadia, Gerhards, Nora M., Albulescu, Irina C., Vreman, Sandra, Gonzales, José L., Maas, Riks, van Kuppeveld, Frank J.M., Soema, Peter, Bosch, Berend-Jan, Peeters, Ben P.H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Authors. Published by Elsevier Ltd. 2022
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257146/ https://www.ncbi.nlm.nih.gov/pubmed/35820941 http://dx.doi.org/10.1016/j.vaccine.2022.07.005

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