Autoimmune Hepatitis Associated With Cryoglobulinemic Vasculitis

Cryoglobulinemic vasculitis presents liver abnormalities usually associated with hepatitis C. We report a case of a 27-year-old woman with cryoglobulinemia and liver dysfunction secondary to autoimmune hepatitis. The patient developed purpura on the lower extremities and elevated aminotransferases....

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Autores principales: Gouveia, Pedro Alves da Cruz, Leal, Maria Teresa de Souza Portela, Rampche, Sylene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257299/
https://www.ncbi.nlm.nih.gov/pubmed/35800298
http://dx.doi.org/10.14309/crj.0000000000000804
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author Gouveia, Pedro Alves da Cruz
Leal, Maria Teresa de Souza Portela
Rampche, Sylene
author_facet Gouveia, Pedro Alves da Cruz
Leal, Maria Teresa de Souza Portela
Rampche, Sylene
author_sort Gouveia, Pedro Alves da Cruz
collection PubMed
description Cryoglobulinemic vasculitis presents liver abnormalities usually associated with hepatitis C. We report a case of a 27-year-old woman with cryoglobulinemia and liver dysfunction secondary to autoimmune hepatitis. The patient developed purpura on the lower extremities and elevated aminotransferases. The investigation of hepatitis C was negative. Autoimmune hepatitis was confirmed by positive ANA, hypergammaglobulinemia, and compatible histological changes. Treatment with prednisone and azathioprine regressed cutaneous vasculitis and decreased aminotransferases. This case describes a rare association of cryoglobulinemic vasculitis and autoimmune hepatitis.
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spelling pubmed-92572992022-07-06 Autoimmune Hepatitis Associated With Cryoglobulinemic Vasculitis Gouveia, Pedro Alves da Cruz Leal, Maria Teresa de Souza Portela Rampche, Sylene ACG Case Rep J Case Report Cryoglobulinemic vasculitis presents liver abnormalities usually associated with hepatitis C. We report a case of a 27-year-old woman with cryoglobulinemia and liver dysfunction secondary to autoimmune hepatitis. The patient developed purpura on the lower extremities and elevated aminotransferases. The investigation of hepatitis C was negative. Autoimmune hepatitis was confirmed by positive ANA, hypergammaglobulinemia, and compatible histological changes. Treatment with prednisone and azathioprine regressed cutaneous vasculitis and decreased aminotransferases. This case describes a rare association of cryoglobulinemic vasculitis and autoimmune hepatitis. Wolters Kluwer 2022-07-05 /pmc/articles/PMC9257299/ /pubmed/35800298 http://dx.doi.org/10.14309/crj.0000000000000804 Text en © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gouveia, Pedro Alves da Cruz
Leal, Maria Teresa de Souza Portela
Rampche, Sylene
Autoimmune Hepatitis Associated With Cryoglobulinemic Vasculitis
title Autoimmune Hepatitis Associated With Cryoglobulinemic Vasculitis
title_full Autoimmune Hepatitis Associated With Cryoglobulinemic Vasculitis
title_fullStr Autoimmune Hepatitis Associated With Cryoglobulinemic Vasculitis
title_full_unstemmed Autoimmune Hepatitis Associated With Cryoglobulinemic Vasculitis
title_short Autoimmune Hepatitis Associated With Cryoglobulinemic Vasculitis
title_sort autoimmune hepatitis associated with cryoglobulinemic vasculitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257299/
https://www.ncbi.nlm.nih.gov/pubmed/35800298
http://dx.doi.org/10.14309/crj.0000000000000804
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