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Adipose-derived exosomes block muscular stem cell proliferation in aged mouse by delivering miRNA Let-7d-3p that targets transcription factor HMGA2

Sarcopenia is an aging-associated attenuation of muscular volume and strength and is the major cause of frailty and falls in elderly individuals. The number of individuals with sarcopenia is rapidly increasing worldwide; however, little is known about the underlying mechanisms of the disease. Sarcop...

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Detalles Bibliográficos
Autores principales:	Itokazu, Maki, Onodera, Yuta, Mori, Tatsufumi, Inoue, Shinji, Yamagishi, Kotaro, Moritake, Akihiro, Iwawaki, Natsumi, Shigi, Kanae, Takehara, Toshiyuki, Higashimoto, Yuji, Akagi, Masao, Teramura, Takeshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257422/ https://www.ncbi.nlm.nih.gov/pubmed/35679898 http://dx.doi.org/10.1016/j.jbc.2022.102098

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