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Repair of common arterial trunk: palliation and delayed correction as a viable alternative strategy in selected patients

OBJECTIVES: Primary repair of common arterial trunk (CAT) is burdened by high mortality rates, especially in the presence of multiple risk factors. Timing, possible palliative methods, optimal management of associated cardiac lesions and handling of a poor preoperative state are still under discussi...

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Autores principales: Cuomo, Michela, Purbojo, Ariawan, Blumauer, Robert, Schöber, Martin, Wällisch, Wolfgang, Dittrich, Sven, Cesnjevar, Robert Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257668/
https://www.ncbi.nlm.nih.gov/pubmed/34718491
http://dx.doi.org/10.1093/ejcts/ezab455
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author Cuomo, Michela
Purbojo, Ariawan
Blumauer, Robert
Schöber, Martin
Wällisch, Wolfgang
Dittrich, Sven
Cesnjevar, Robert Anton
author_facet Cuomo, Michela
Purbojo, Ariawan
Blumauer, Robert
Schöber, Martin
Wällisch, Wolfgang
Dittrich, Sven
Cesnjevar, Robert Anton
author_sort Cuomo, Michela
collection PubMed
description OBJECTIVES: Primary repair of common arterial trunk (CAT) is burdened by high mortality rates, especially in the presence of multiple risk factors. Timing, possible palliative methods, optimal management of associated cardiac lesions and handling of a poor preoperative state are still under discussion. METHODS: We retrospectively analysed all patients who underwent surgery for CAT in our institution between 2008 and November 2020. We included 22 patients, 11 of whom received primary correction (PC) and 11 of whom underwent initial palliation by partial repair, leaving the ventricular septal defect open and connecting the right ventricle to the pulmonary arteries with a small valveless right ventricle-to-pulmonary artery conduit. A delayed correction (DC) was performed after 11.5 ± 3.6 months. RESULTS: The overall operative mortality was 4.5%; 1 patient (affected by severe truncal valve stenosis and presenting in a poor state preoperatively) in the DC group died after palliation. The incidence of postoperative pulmonary hypertensive crisis was significantly higher in the PC group (P = 0.027). No patient from either group required postoperative extracorporeal support. Survival rates after 6 years differed slightly (PC group, 90%; DC group, 70%; log-rank = 0.270). CONCLUSIONS: PC of CAT remains an optimal surgical approach for patients with an expected low mortality. However, our data support palliation and DC as a suitable alternative strategy, especially in the presence of significant risk factors like interrupted aortic arch, poor preoperative condition or complex surgical anatomy.
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spelling pubmed-92576682022-07-06 Repair of common arterial trunk: palliation and delayed correction as a viable alternative strategy in selected patients Cuomo, Michela Purbojo, Ariawan Blumauer, Robert Schöber, Martin Wällisch, Wolfgang Dittrich, Sven Cesnjevar, Robert Anton Eur J Cardiothorac Surg Congenital OBJECTIVES: Primary repair of common arterial trunk (CAT) is burdened by high mortality rates, especially in the presence of multiple risk factors. Timing, possible palliative methods, optimal management of associated cardiac lesions and handling of a poor preoperative state are still under discussion. METHODS: We retrospectively analysed all patients who underwent surgery for CAT in our institution between 2008 and November 2020. We included 22 patients, 11 of whom received primary correction (PC) and 11 of whom underwent initial palliation by partial repair, leaving the ventricular septal defect open and connecting the right ventricle to the pulmonary arteries with a small valveless right ventricle-to-pulmonary artery conduit. A delayed correction (DC) was performed after 11.5 ± 3.6 months. RESULTS: The overall operative mortality was 4.5%; 1 patient (affected by severe truncal valve stenosis and presenting in a poor state preoperatively) in the DC group died after palliation. The incidence of postoperative pulmonary hypertensive crisis was significantly higher in the PC group (P = 0.027). No patient from either group required postoperative extracorporeal support. Survival rates after 6 years differed slightly (PC group, 90%; DC group, 70%; log-rank = 0.270). CONCLUSIONS: PC of CAT remains an optimal surgical approach for patients with an expected low mortality. However, our data support palliation and DC as a suitable alternative strategy, especially in the presence of significant risk factors like interrupted aortic arch, poor preoperative condition or complex surgical anatomy. Oxford University Press 2021-10-29 /pmc/articles/PMC9257668/ /pubmed/34718491 http://dx.doi.org/10.1093/ejcts/ezab455 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Congenital
Cuomo, Michela
Purbojo, Ariawan
Blumauer, Robert
Schöber, Martin
Wällisch, Wolfgang
Dittrich, Sven
Cesnjevar, Robert Anton
Repair of common arterial trunk: palliation and delayed correction as a viable alternative strategy in selected patients
title Repair of common arterial trunk: palliation and delayed correction as a viable alternative strategy in selected patients
title_full Repair of common arterial trunk: palliation and delayed correction as a viable alternative strategy in selected patients
title_fullStr Repair of common arterial trunk: palliation and delayed correction as a viable alternative strategy in selected patients
title_full_unstemmed Repair of common arterial trunk: palliation and delayed correction as a viable alternative strategy in selected patients
title_short Repair of common arterial trunk: palliation and delayed correction as a viable alternative strategy in selected patients
title_sort repair of common arterial trunk: palliation and delayed correction as a viable alternative strategy in selected patients
topic Congenital
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257668/
https://www.ncbi.nlm.nih.gov/pubmed/34718491
http://dx.doi.org/10.1093/ejcts/ezab455
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