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Procyanidin B2 suppresses hyperglycemia-induced renal mesangial cell dysfunction by modulating CAV-1-dependent signaling

The dysfunction of renal mesangial cells (MCs) is a hallmark of diabetic kidney disease (DKD), which triggers glomerulosclerosis leading to end-stage renal disease. Procyanidin B2 (PB2), the main component of proanthocyanidin, is well known for its antioxidant and anti-inflammatory effects; however,...

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Detalles Bibliográficos
Autores principales:	Yin, Jun, Wang, Ke, Zhu, Xue, Lu, Guoyuan, Jin, Donghua, Qiu, Junsi, Zhou, Fanfan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257762/ https://www.ncbi.nlm.nih.gov/pubmed/35837062 http://dx.doi.org/10.3892/etm.2022.11423

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