Cargando…

Extracellular Vesicles Derived From Ex Vivo Expanded Regulatory T Cells Modulate In Vitro and In Vivo Inflammation

Extracellular vehicles (EVs) are efficient biomarkers of disease and participate in disease pathogenesis; however, their use as clinical therapies to modify disease outcomes remains to be determined. Cell-based immune therapies, including regulatory T cells (Tregs), are currently being clinically ev...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thome, Aaron D., Thonhoff, Jason R., Zhao, Weihua, Faridar, Alireza, Wang, Jinghong, Beers, David R., Appel, Stanley H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258040/ https://www.ncbi.nlm.nih.gov/pubmed/35812435 http://dx.doi.org/10.3389/fimmu.2022.875825

Ejemplares similares

Ex vivo expansion of dysfunctional regulatory T lymphocytes restores suppressive function in Parkinson’s disease
por: Thome, Aaron D., et al.
Publicado: (2021)

Restoring regulatory T-cell dysfunction in Alzheimer’s disease through ex vivo expansion
por: Faridar, Alireza, et al.
Publicado: (2020)

Ex vivo expanded human regulatory T cells modify neuroinflammation in a preclinical model of Alzheimer’s disease
por: Faridar, Alireza, et al.
Publicado: (2022)

Elevated acute phase proteins reflect peripheral inflammation and disease severity in patients with amyotrophic lateral sclerosis
por: Beers, David R., et al.
Publicado: (2020)

Serum programmed cell death proteins in amyotrophic lateral sclerosis
por: Beers, David R., et al.
Publicado: (2021)

Tregs Attenuate Peripheral Oxidative Stress and Acute Phase Proteins in ALS
por: Beers, David R., et al.
Publicado: (2022)

Functional alterations of myeloid cells during the course of Alzheimer’s disease
por: Thome, Aaron D., et al.
Publicado: (2018)

Immunosuppressive Functions of M2 Macrophages Derived from iPSCs of Patients with ALS and Healthy Controls
por: Zhao, Weihua, et al.
Publicado: (2020)

Expanded autologous regulatory T-lymphocyte infusions in ALS: A phase I, first-in-human study
por: Thonhoff, Jason R., et al.
Publicado: (2018)

In vivo Prevention of Transplant Arteriosclerosis by ex vivo Expanded Human Regulatory T Cells
por: Nadig, Satish N., et al.
Publicado: (2010)

Combined Regulatory T-Lymphocyte and IL-2 Treatment Is Safe, Tolerable, and Biologically Active for 1 Year in Persons With Amyotrophic Lateral Sclerosis
por: Thonhoff, Jason R., et al.
Publicado: (2022)

Ex vivo expanded autologous polyclonal regulatory T cells suppress inhibitor formation in hemophilia
por: Sarkar, Debalina, et al.
Publicado: (2014)

A phase 1 open-label pilot study of low-dose interleukine-2 immunotherapy in patients with Alzheimer’s disease
por: Faridar, Alireza, et al.
Publicado: (2023)

Neuroprotective effects of ex vivo-expanded regulatory T cells on trimethyltin-induced neurodegeneration in mice
por: Park, Seon-Young, et al.
Publicado: (2022)

Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis
por: Beers, David R., et al.
Publicado: (2011)

Prevention of Allogeneic Cardiac Graft Rejection by Transfer of Ex Vivo Expanded Antigen-Specific Regulatory T-Cells
por: Takasato, Fumika, et al.
Publicado: (2014)

An in vivo model for extracellular vesicle–induced emphysema
por: Margaroli, Camilla, et al.
Publicado: (2022)

An ex vivo model of interactions between extracellular vesicles and peripheral mononuclear blood cells in whole blood
por: Rodriguez, Blanca V., et al.
Publicado: (2023)

A Phase I Clinical Trial with Ex Vivo Expanded Recipient Regulatory T cells in Living Donor Kidney Transplants
por: Mathew, James M., et al.
Publicado: (2018)

Suppression of Glomerulonephritis in NZB/NZW Lupus Prone Mice by Adoptive Transfer of Ex Vivo Expanded Regulatory T Cells
por: Scalapino, Kenneth J., et al.
Publicado: (2009)

Increased Motility and Suppression of Ex Vivo–Expanded Regulatory T Cells Designed for Adoptive Transfer Therapy in Ulcerative Colitis
por: Müller, Tanja M., et al.
Publicado: (2023)

Radioiodine labeling and in vivo trafficking of extracellular vesicles
por: Hong, Chae Moon, et al.
Publicado: (2021)

Fluorescence Tracking of Small Extracellular Vesicles In Vivo
por: Chen, Yanxia, et al.
Publicado: (2023)

Watermelon‐Derived Extracellular Vesicles Influence Human Ex Vivo Placental Cell Behavior by Altering Intestinal Secretions
por: Timms, Kate, et al.
Publicado: (2022)

Placenta-derived extracellular vesicles from preeclamptic and healthy pregnancies impair ex vivo vascular endothelial function
por: Villalobos-Labra, Roberto, et al.
Publicado: (2022)

Ex vivo and in vivo generation of neutrophil extracellular traps by neutrophils from septic patients
por: Takeyama, N, et al.
Publicado: (2015)

Non‐Invasive imaging of extracellular vesicles: Quo vaditis in vivo?
por: Arifin, Dian R., et al.
Publicado: (2022)

Extracellular Vesicles Generated by Gram-Positive Bacteria Protect Human Tissues Ex Vivo From HIV-1 Infection
por: Costantini, Paolo E., et al.
Publicado: (2022)

All-in-One Nanowire Assay System for Capture and Analysis of Extracellular Vesicles from an ex Vivo Brain Tumor Model
por: Chattrairat, Kunanon, et al.
Publicado: (2023)

Extracellular Histones Induce Chemokine Production in Whole Blood Ex Vivo and Leukocyte Recruitment In Vivo
por: Westman, Johannes, et al.
Publicado: (2015)

Therapeutic Potential of Ex Vivo Expanded γδ T Cells against Osteosarcoma Cells
por: Ko, Yunmi, et al.
Publicado: (2022)

Engineering Extracellular Vesicles to Target Pancreatic Tissue In Vivo
por: Komuro, Hiroaki, et al.
Publicado: (2021)

In Vivo Characterization of Endogenous Cardiovascular Extracellular Vesicles in Larval and Adult Zebrafish
por: Scott, Aaron, et al.
Publicado: (2021)

Editorial: miRNA Regulatory Pathways in Metazoans. Advances From in vivo and ex vivo Studies
por: Amar, Laurence, et al.
Publicado: (2019)

Ex vivo-expanded human CD19(+)TIM-1(+) regulatory B cells suppress immune responses in vivo and are dependent upon the TIM-1/STAT3 axis
por: Shankar, S., et al.
Publicado: (2022)

Ex Vivo and In Vivo Properties of an Injectable Hydrogel Derived From Acellular Ear Cartilage Extracellular Matrix
por: Gong, Danni, et al.
Publicado: (2021)

Technical Considerations in Ex Vivo Human Regulatory T Cell Migration and Suppression Assays
por: Irekeola, Ahmad Adebayo, et al.
Publicado: (2020)

Large and small extracellular vesicles released by glioma cells in vitro and in vivo
por: Yekula, Anudeep, et al.
Publicado: (2019)

Ex Vivo Expanded Human Regulatory T Cells Can Prolong Survival of a Human Islet Allograft in a Humanized Mouse Model
por: Wu, Douglas C., et al.
Publicado: (2013)

Abstract 38: Ex Vivo Expanded Regulatory T Cells Combined With Short-term Costimulation Blockade To Prevent Rejection Of Vascularized Composite Allografts
por: Grzelak, Michael J., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_0jq1cpprr7kds90lgb92lfufg0